Introduction to Randomized Controlled Clinical Trials

ISBN-13: 9781138469501 / Angielski / Twarda / 2017

Matthews, John N. S.

Opis

Focusing on the important role that statistical methods play in the analysis of the data collected as well as in the overall clinical trial process, this title provides an introduction to clinical trials. It features examples, exercises, and material on binary outcomes and survival analysis. It features various real examples taken from The Lancet.

Spis treści

What is a Randomized Controlled Trial? Bias. How Many Patients Do I Need? Methods of Allocation. Assessment, Blinding and Placebos. Analysis of Results. Further Analysis: Binary and Survival Data. Monitoring Accumulating Data. Subgroups and Multiple Outcomes. Protocols and Protocol Deviations. Some Special Designs: Crossovers, Equivalence and Clusters. Meta-Analyses of Clinical Trials. Further Reading. Solutions to Exercises. References.

O autorze

John N.S. Matthews