Introduction to Biological Networks

ISBN-13: 9780367380137 / Angielski / Miękka / 2019 / 335 str.

Alpan Raval; Animesh Ray

Opis

With many examples throughout and clear explanations of key concepts, this book focuses on the genetic interaction networks as a paradigm for interpreting the complexity of molecular biology at a genomic scale. The authors describe the experimental methods used to discover and test networks of interaction among biological molecules. They also present computational methods for predicting the interaction networks, discuss general mechanisms of network formation and evolution, and explore the application of network approaches to important problems in biology and medicine.

Spis treści

The Living Interactome. Experimental Inference of Interactions. Prediction of Physical Interactions. Metabolic Networks and Genetic Interactions. Testing Inferred Networks. Small Model Networks. Tractable Models of Large Networks. Network Modularity and Robustness. Networks and Disease.

O autorze

Raval, Alpan; Ray, Animesh