Introduction to Biliary Atresia

ISBN-13: 9789811621598 / Angielski / Twarda / 2021 / 350 str.

Masaki Nio

Spis treści

Biliary Atresia: A Historical Overview

History of The Japanese Biliary Atresia Society (JABS)

Japanese Biliary Atresia Registry (JBAR)

Pathogenesis: Overview

Pathogenesis: Genetics/Epigenetics

Pathogenesis: Viral Infection

Pathogenesis: Maternal Microchimerism

Epidemiology: Incidence and Gender Ratio

Epidemiology: Ethnic Variations/Family Histories/Heredity

Epidemiology: Gestational Age/Birth Weight /Associated Anomalies

Classifications

Mass Screening

Stool Color Card System

Prenatal Diagnosis and Signs/Symptoms

Intracranial Hemorrhage

Pathology

Biomarkers 

Differential Diagnosis

Diagnostic Modalities

Preoperative Management and Direct Cholangiography

Operative Procedures: Open Kasai Procedure

Operative Procedures: Laparoscopic Kasai Procedure

Operative Procedures: Re-do Kasai Procedure

Operative Procedures: Cadaveric Liver Transplantation

Operative Procedures: Living Donor Liver Transplantation

Medical Treatment: UDCA/Steroid

Medical Treatment: Kampo Medicine

Prevention/Treatment of Postoperative Cholangitis

Nutritional Support

Protocols of Follow-up Management

Prognostic Indicators

Long-term Complications: Gastro-Esophageal Varices

Long-term Complications: Hypersplenism

Long-term Complications: Cholangitis/Gall Stones

Long-term Complications: Hepatopulmonary Syndrome

Long-term Complications: Portopulmonary Hypertension

Long-term Complications: Liver Cirrhosis/Hepatic Encephalopathy 

Long-Term Results, General

Long-Term Results, Deformity of Intrahepatic Bile Ducts

Long-Term Results, Social Performance

Long-Term Results, Liver Transplantation

Biliary Atresia and Pregnancy/Delivery

Biliary Atresia and Malignancy

Future Prospects

Transition in Biliary Atresia

Society of Patients and Families

Clinical Guidelines for Biliary Atresia

O autorze

Masaki Nio, M.D., Ph.D., ACSF

Masaki Nio is Professor and Chief of Pediatric Surgery at Tohoku University Graduate School of Medicine and Director of Pediatric Medical Center of Tohoku University Hospital. In 1981, he completed a M.D. course at Tohoku University School of Medicine. In 1983, he joined the Second Department of Surgery, Tohoku University Hospital, which Professor Morio Kasai presided over from 1963 to 1986. In 1987, he completed a Ph.D. course in Pediatric Surgery at Tohoku University Graduate School of Medicine. From 1991 to 1993, he worked as a research fellow in Children’s Hospital of Los Angeles, USA. He served as the President of Japanese Society of Pediatric Surgeons, a Board Member of Japan Surgical Society, a Board Member of Pacific Association of Pediatric Surgeons, the Chairman of Japanese Biliary Atresia Society, and so on. He has been a secretary general of Japanese Biliary Atresia Society since 2008.

Blurb

This book offers a comprehensive overview of the latest standard medical procedures and surgical techniques for biliary atresia (BA), as well as the perioperative care, long-term follow-up and transitions. Experts on pediatrics in such fields as hepatology, surgery, pathology, and liver transplantation present their research findings and analyses of this rare and intractable disease of unknown etiology. In Japan, shared experience and sound understanding based on conferences and guidelines have led to standardization of management and clinical care and, as a result, better outcomes.

Providing insights into improving surgical outcomes, and including special chapters focusing on social support systems for patients and families as well as recent advances in early diagnosis, this book a valuable resource for medical professionals around the globe who are involved in treating biliary atresia. It is especially useful for pediatric hepatologists, pediatric surgeons and transplant surgeons.