Intra-Operative Neuropathology for the Non-Neuropathologist: A Case-Based Approach

ISBN-13: 9781493940455 / Angielski / Miękka / 2016 / 170 str.

Cynthia T. Welsh

Opis

This book examines the advantages of clinical-radiologic-pathologic correlation in neuropathology specimens, especially in the intra-operative consultation. Covers frozen sections and cytologic preparations, and includes many diagrams, tables and figures.

Recenzje

From the reviews:

"This book takes a case-based approach to the interpretation of frozen sections and smears for the non-neuropathologist. ... this book is intended for non-neuropathologists. ... will definitely keep it as a reference on my shelf of important books. The location-based development of differential diagnoses and the inclusion of neuroimaging characteristics make this the perfect book for the non-neuropathology fellowship-trained pathologist. I highly recommend it as a worthy addition to the books available in the frozen section area of any practice." (Maura F. O'Neil, Doody's Review Service, April, 2012)

Spis treści

Chapter 1. The role of clinical-pathologic correlation, and use of cytologic preparations in intra-operative neuropathology consultation. Dr. Welsh

Chapter 2. Neuroradiology as a tool in neuropathologic diagnosis. Dr. Rumboldt

Chapter 3. The supratentorial mass in an adult: Drs. Welsh and Smith

Intra-axial:

A. A 36 year old male with an incidental frontal lesion – astrocytoma, low grade

B. A 40 year old female with new-onset seizures - oligodendroglioma

C. A 74 year old female with headache and left hemiparesis - GBM

D. A 50 year old male with seizure and unilateral weakness - met

E. A 70 year old male dense hemiparesis and history of kidney transplant – infarct

F. A 74 year old female with headache, confusion and personality change - PCNSBCL

G. A 65 year old male with dizziness and left arm/leg weakness - gliosarcoma

H. A 39 year old male with new-onset seizures – ganglioglioma

I. A 25 year old female with headache, nausea/vomiting, blurry vision – neurocytoma

Extra-axial:

A. A 30 year old female with headaches and visual changes – meningioma

Chapter 4. The infratentorial intra-axial tumor. Drs. Welsh and Smith

In a child:

A. A 15 year old female with headache, nausea, and vomiting - pilocytic

B. A 12 year old male with headache, irritability, and vertigo - medulloblastoma

C. A 12 year old female with headache, nausea/vomiting and vertigo - ependymoma

In an adult:

A.A 60 year old male with headache and ataxia – hemangioblastoma

Chapter 5. The base of skull (including pineal and sella turcica regions) lesion. Dr. Welsh

In an adult:

A. A 27 year old female with visual disturbance and headaches – pituitary adenoma

B. A 56 year old female with headache, dizziness, double vision - plasmacytoma

C. A 55 year old male with complaints of swallowing difficulties – chordoma

D.A 23 year old female with nasal congestion and forehead pain – olfactory neuroblastoma

In a child/young adult:

A. An 18year old female with headache – pineoblastoma

B.A 20 year old male with headache, nausea, visual changes – germ cell tumor

Chapter 6. The spinal neoplasm. Dr. Welsh

A. A 44 year male with leg and back pain – myxopapillary ependymoma

B. A 36 year old male with leg weakness and history of NF1- schwannoma

Blurb

 This volume acquaints the non-neuropathologist with the advantages of clinical-radiologic-pathologic correlation in neuropathology specimens, particularly in the intra-operative environment. This volume covers the enormous and sometimes insurmountable artifacts involed with freezing tissue, especially central nervous system tissue and how a good cytology preparation can add to, or even supply in isolation, a diagnosis. The text presents how to perform, and stain the cytologic preparations, and how to interpret them. The advantages and disadvantages of both frozen sections and cytologic preparations of various kinds are discussed. The presentation and format is very visual with diagrams, tables (including pearls and pitfalls), and many figures (therefore easy reading).

An introductory chapter presents the pros and cons of supplemental cytology, the advantages and disadvantages of frozen sections, and the artifacts in both. Also included is an argument for knowing what the scans reveal and the impact of relevant patient history. The volume uses a case-based approach to show correlation between scan, history, frozen section and cytologic preparations.

With the combination of extensive correlation of scans, cytology and frozen section with differential diagnosis, and analysis of the information crucial to the neurosurgeon in a case-based approach and with a special chapter written by a neuroradiologist, this volume is unique in presentation and utility and will be of great value to the trainee in pathology (residents/fellows), and practicing pathologists who include neuropathology in their practice, but do not have formal fellowship training in neuropathology.