Interactions of Polymers with Bioactive and Corrosive Media

ISBN-13: 9789067641623 / Angielski / Twarda / 1994 / 298 str.

A. L. Iordanskifi; Gennadifi Efremovich Zaikov; T. E. Rudakova

Opis

The successful applications of synthetic polymers in medicine depend mainly on their physico-chemical and special characteristics. This book deals mainly with the kinetic and structural aspects which are essential for the realization of these characteristics.

Spis treści

Part 1 Kinetic aspects of polymer interaction with components of aggressive media: macrokinetic correlations of the chemical degradation processes; degradation of polymeric materials of in-homogeneous structure; physical model of polymeric article degradation process. Part 2 Water diffusion in polymer systems of different hydrophilicity: water sorption in hydrophobic polymers; water diffusion in hydrophoblic polymers; equilibrium water sorption in hydrophilic polymers; water diffusion in hydrophilic polymers; water diffusion in moderately hydrophilic polymers. Part 3 Transport processes in the system polymer-chemical (biological) medium: diffusion features of ionized low-molecular compounds in polymer systems; description of multi-component diffusion in polymers through thermodynamics of irreversible processes; theories describing the connection of diffusion co-efficients of medium components with volume contents in polymers; electrolyte state in polymers; surface phenomena complicating diffusion process. Part 4 The role of diffusion processes under controlled release of biologically active substances from polymer therapeutic systems: diffusion-controlled therapeutic systems; the influence of solvent diffusion on the rate of release of medicinal substance; diffusion polymer systems of special purpose; erosive therapeutic systems. Part 5 Diffusion and adsorption of plasma proteins - the processes, characterizing initial stage of polymer-blood interactions: the role of primary adsorption and diffusion of proteins in the general scheme of polymer-blood interaction; thermodynamic aspect of protein adsorption; surface energy of polymers and plasma protein adsorption; structural aspect of plasmic protein adsorption; medium acidity influence on protein adsorption; the kinetic aspect of adsorption; the diffusive-kinetic model of protein adsorption on polymer surface. Part 6 Polymer biodegradation - kinetics and mechanisms. Part 7 Degradation and medico-biological estimation of polymers in biological and model chemical media. Part 7 Mechanical reliability of polymers in physical, chemical and biological media (Part contents)

O autorze

Zaikov\, Gennady; Iordanskii\, ; Rudakova\,