The INTEGRATED SCIENCE Book series aims to publish the results of the most updated ideas and reviews in transdisciplinarity fields, to highlight the integration of different disciplines, including formal sciences, physical-chemical sciences, engineering, biological sciences, medical sciences, and social sciences. The whole world is suffering from complex problems; these are borderless problems; so, a borderless solution could be the solution for such complex problems. The “INTEGRATED SCIENCE: Science without Borders” is the first volume of the INTEGRATED SCIENCE Book series. It focuses on the human as an integrated system and finding solutions for the problems facing humanity. For its purpose, it introduces a kind of science, which is called integrated science and portrays results from every effort trying to integrate separate subjects. Integration of science with integral human knowledge, ancient science with modern science, and quantity with quality are a few examples of such efforts. Some difficulty might, however, lie in integrating knowledge systems. In this edited book, art and artificial intelligence reveal to us their different methods of work to overcome ambitions and become applicable to the world system full of unpredictable challenges. Art offers a lens to see the beauty of infinite complexity. The resultant artistic background would permit the perfect programming and bioengineering of biological systems, which we could never do by direct eye viewing. Networking is the spot where the crossing of formal, biological, medical, and social sciences with artificial intelligence takes place. By working within a network, individual thinking to the old unresolved problems reduces to simulation and bioengineering, a relatively effortless route for innovation, creativity, and altruism. In this manner, it would be understandable that there is an obvious way to speed up the growth of science – that is, moving on the edge of the intersection between knowledge-based systems. The INTEGRATED SCIENCE Book series is to provide an overview of the essential elements of integrated science. The unique aspect of this series, privileging it from other books, is covering all aspects of science as a true one nature.