Integrated Omics Approaches to Infectious Diseases

ISBN-13: 9789811606939 / Angielski / Miękka / 2022

Opis

This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.

Spis treści

Chapter 1_Genomic Classification of Human Pathogens. –Chapter 2_Metagenomics of Human Microbiome. –Chapter 3_Genomic Landscape of Novel Coronavirus (2019-Ncov) Towards Better Diagnosis and Efficient Antiviral Therapies. –Chapter 4_Deciphering the Role of Epigenetic Reprogramming In Host-Pathogen Interactions. –Chapter 5_Applications of Next Generation Sequencing In Infectious Pathogens. –Chapter 6_Bioinformatics Applications in Human Pathogens. –Chapter 7_ Non-Coding RNA Profiling: Potential Application in Infectious Diseases. –Chapter 8_ Microarrays: A Road Map to Uncover Host Pathogen Interactions. –Chapter 9_RNA Sequencing as Strategy to Understand Pathogenesis. –Chapter 10_ Non-Coding RNA as Drug Target against Infectious Diseases. –Chapter 11_ Emerging Transcriptional Approach for Identification of Drug Targets in Human Pathogens. –Chapter 12_ Proteogenomics Applications in Human Pathogens.–Chapter 13_Proteomic Strategies for Understanding Host Pathogen Interactions.–Chapter 14_Antimicrobial and Therapeutic Peptides. –Chapter 15_ Structural Proteomics Guided Design of Antimicrobial Drugs and Vaccines. –Chapter 16_Mechanism of Action of Antimicrobial Agents against Clinically Important Pathogens: A Proteomic Approach. –Chapter 17_Application of Lipidomics in Understanding Host Pathogen Interaction. –Chapter 18_Metabolomics: Advances and Applications In Human Pathogens. –Chapter 19_Host-Pathogen Interactions: Nature Inspired Sialic Acid Based Biointerface Materials. –Chapter 20_Nanoparticles as Therapeutic Nanocargos Affecting Epigenome of Microbial Biofilms. –Chapter 21_Challenges and Prospects in Omics Approach to Pathogens

O autorze

Dr. Saif Hameed is currently an Associate Professor at Amity Institute of Biotechnology, Amity University, Haryana. Dr. Hameed did his Bachelor’s from the University of Delhi and Masters from Jamia Hamdard and completed his doctoral studies in Life Sciences from Jawaharlal Nehru University. He also worked as a visiting scholar in Institute für Mikrobiologie, Heinrich-Heine-Universität, Düsseldorf, Germany, in 2008. Dr. Hameed has received the Young Scientist award from the Science and Engineering Research Board, Department of Science and Technology, New Delhi. Dr. Hameed is actively engaged in research in infectious diseases particularly multidrug resistance (MDR) in pathogenic fungi. He has around 50 peer-reviewed papers to his credit in high repute journals, 3 books, 21 book chapters, and 25 popular articles, with 2 of them as ‘cover story’ and guided 4 doctoral students. He is a life member of the Association of Microbiologists of India (AMI) and the International Society for Infectious Diseases (ISID).

Dr. Zeeshan Fatima is currently working as Associate Professor at Amity Institute of Biotechnology, Amity University, Haryana. Dr. Fatima did her Bachelor’s and Masters from Banaras Hindu University and earned her doctoral degree in Biochemistry from Aligarh Muslim University. She has held research positions under nationally and internationally funded research projects, including her Research Associateship at BHU and JNU and postdoctoral training from the University of Cincinnati, Ohio, USA. Dr. Fatima has received two Young Scientist awards under Fast Track and Women Scientist Schemes, respectively, from the Science and Engineering Research Board, Department of Science and Technology, New Delhi. She is actively engaged in infectious diseases research, particularly on multidrug resistance in human pathogens, Mycobacterium tuberculosis and Candida albicans. She has 3 books and around 45 peer-reviewed papers to her credit in journals of high repute and supervised 4 doctoral thesis. She is a life member of the Association of Microbiologists of India (AMI), Society of Biological Chemists (SBC), India and the International Society for Infectious Diseases (ISID).