Integrated Diagnostics and Theranostics of Thyroid Diseases

ISBN-13: 9783031352126 / Angielski / Twarda / 2023

Opis

This open access book provides basic concepts on Integrated Diagnostics and Theranostics with special emphasis on different human thyroid diseases. Thyroid diseases  are increasingly detected (incidentally in many cases) but are clinically negligible in a significant proportion of patients. Accordingly, it is urgent to move from the simple disease detection to a reliable disease characterization in order to concentrate efforts on patients in need of tailored disease management. The current scenario of in vitro and in vivo diagnostics, is fastly moving toward the Integrated Diagnostics (i.e. convergence of imaging, pathology and laboratory tests with advanced information technology). Furthermore, the integration of different information will aid clinicians to properly select treatments and stratify patients’ prognosis over time. Theranostics is a perfect paradigm of such integrated approach and radioiodine, indicated for benign and malignant thyroid disease management, was the first and is still the mostly used theranostic agent in medicine.Featuring basics concepts and clinical cases discussions the Atlas will be an invaluable tool for clinicians, laboratory specialists, imaging physicians and biomedical technologists involved in diagnosis and therapy of thyroid diseases.

Spis treści

Integrated Diagnostics: the future of Diagnostic Medicine?

Artificial intelligence and machine learning in integrated diagnostic

Thyroid dysfunctions: integrate to simplify

Integrated thyroid imaging: ultrasound and scintigraphy

Non-invasive imaging-biomarkers of thyroid nodules with indeterminate cytology

Radioiodine Theranostics of benign thyroid diseases

Radioiodine Theranostics of differentiated thyroid carcinoma

Biomarkers and molecular imaging in postoperative DTC management

Definition of radioactive iodine refractory thyroid cancer AND REDIFFERENTIATION STRATEGIES

Integrated Diagnostics and Theranostics of Medullary Thyroid Carcinoma and Related Syndromes 

O autorze

Prof Giovanella serves as Professor of Nuclear Medicine at University Hospital and University of Zürich and as Scientific Advisor of the Interdisciplinary Thyroid Center at the University Hospital of Zürich (Switzerland). He’s the Chairman of the Thyroid Committee-European Assocition of Nuclear Medicine and the Chairman of the Thyroid Working Group-Swiss Society of Nuclear Medicine. He also serves as Chairman of the Clinic of Nuclear Medicine and Molecular Imaging - Imaging Institute of Southern Switzerland in Bellinzona (Switzerland) and Consultant for integrated endocrine diagnostics at Synlab Switzerland (Lucerne).

His clinical and scientific activities are mainly focused on the diagnosis and treatment of thyroid diseases with emphasis on molecular imaging, theranostics, circulating and predictive “in vivo” and “in vitro”.

He is the author of more than 500 peer-reviewed scientific papers, several book’s chapters and is the editor of five monographic books on thyroid diseases, theranostics and positron emission tomography-based molecular imaging.