Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment

ISBN-13: 9781617377631 / Angielski / Miękka / 2010 / 475 str.

Evanthia Diamanti-Kandarakis; John E. Nestler; Dimitrios Panidis

Opis

Polycystic Ovarian Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. Providing a state-of-the-art analysis of the connection between insulin resistance and PCOS, this book comprehensively covers a range of topics. It provides an up-to-date and balanced overview of PCOS, with specific attention to the role of insulin resistance in its pathogenesis. It also examines diet and lifestyle factors in the aetiology and management of PCOS.

Recenzje

From the reviews:

"This volume provides an up to date comprehensive review on various aspects of the polycystic ovary syndrome (PCOS), a more and more diagnosed disorder also in adolescent girls. It is divided into 6 parts ... . A well written and informative text." (Pediatric Endocrinology Reviews, Vol. 5 (3), 2008)

"This is an overview of the association between insulin resistance and polycystic ovary syndrome (PCOS) with a special focus on pathogenesis, evaluation, and treatment. The book also focuses on the other metabolic and fertility issues occurring in PCOS. ... Although it can be used by students and residents, it is written primarily for practitioners whose focus is either in endocrinology or obstetrics/gynecology. ... The book is useful and the information is current and relevant." (Monica Mortensen, Doody's Review Service, August, 2007)

Spis treści

1. EVALUATION FOR INSULIN RESISTANCE AND CO-MORBIDITIES RELATED TO INSULIN RESISTANCE IN PCOS Ricardo Azziz, MD, MPH, MBA Dept. of Ob/Gyn, Cedars-Sinai Medical Center, and Depts. of Ob/Gyn and Medicine, The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA 2. FAT DISTRIBUTION AND ADIPOSE PRODUCTS IN PCOS Running title: Adipose products in PCOS Enrico Carmina, M.D. Department of Clinical Medicine, University of Palermo, Palermo, Italy 3. Treatment of Infertility in PCOS: Ovulation Induction Running head: Ovulation Induction in PCOS Authors: Deborah S. Wachs, MD University of California, San Diego School of Medicine Department of Reproduction Medicine *R. Jeffery Chang, MD University of California, San Diego School of Medicine Department of Reproduction Medicine 4. IMAGING STUDIES IN POLYCYSTIC OVARY SYNDROME Sophie JONARD, MD 1, Yann ROBERT, MD 2, Yves ARDAENS, MD 2 and Didier DEWAILLY, MD 1 1 Department of Endocrine Gynaecology and Reproductive Medecine, Hopital Jeanne de Flandre, Centre Hospitalier et Universitaire de Lille, France 2 Department of Radiology, Hopital Jeanne de Flandre, Centre Hospitalier et Universitaire de Lille, France 5. GENES RELATED TO METABOLIC ABNORMALITIES OR INSULIN RESISTANCE IN PCOS SHORT TITLE: Insulin resistance genes in PCOS Héctor F. Escobar-Morreale, MD, PhD Department of Endocrinology, Hospital Ramón y Cajal & Department of Medicine, Universidad de Alcalá, Madrid, Spain 6. ANTI-ANDROGENS Kür_ad Ünlühizarci, M.D. and Fahrettin Kele_timur, M.D. Department of Endocrinology, Erciyes University Medical School, Kayseri, Turkey 7. LIPID ABNORMALITIES IN PCOS Abbreviated title: Lipids and PCOS Djuro Macut, M.D., PhD. Institute of Endocrinology, Diabetes and Diseases of Metabolism, Dr Subotica 13, 11000 Belgrade, Serbia 8. Serine Phosphorylation,Insulin Resistance, and the Regulation OF ANDROGEN SYNTHESIS Running title: Serine phosphorylation, insulin resistance, and steroidogenesis Andrew A. Bremer M.D., Ph.D.*, Walter L. Miller, M.D. Department of Pediatrics, University of California, San Francisco *Supported by Pediatric Endocrinology Training Grant T32 DK07161 9. CHRONIC TREATMENT OF POLYCYSTIC OVARIAN SYNDROME: ORAL CONTRACEPTIVE PILLS Running Title: PCOS and OCP treatment Shahla Nader, M.D. Departments of Obstetrics, Gynecology & Reproductive Sciences and Internal Medicine The University of Texas Medical School - Houston 10. INSULIN SENSITIZING DRUGS FOR THE TREATMENT OF INFERTILITY IN POLYCYSTIC OVARY SYNDROME (Insulin Sensitizing Drugs in PCOS) Cynthia S. Ryan, MDa, John E. Nestler, MDbc aClinical Fellow, Division of Endocrinology and Metabolism, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia bWilliam G. Blackard Professor of Medicine and Chair, Division of Endocrinology and Metabolism, Medical College of Virginia, Virginia Commonwealth University; and cVice Chair Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 11. DIET AND LIFESTYLE FACTORS IN THE AETIOLOGY AND MANAGEMENT OF POLYCYSTIC OVARY SYNDROME R. J. NORMAN1 and L.J. MORAN2 1Research Centre for Reproductive Health and Repromed, The Queen Elizabeth Hospital University of Adelaide South Australia, Australia 2CSIRO Human Nutrition, Kintore Avenue, Adelaide 5000 South Australia, Australia 12. ADRENARCHE: THE INTERRELATIONSHIP OF ANDROGENS/ INSULIN ON THE DEVELOPMENT OF THE METABOLIC SYNDROME/ PCOS Running Head: Adrenarche: Metabolic Syndrome/ PCOS Authors: Sharon E. Oberfield, M.D(1), Natasha Leibel, M.D. (1), Lauren Antler B.A. (1), Miriam Silfen, M.D. (1), Lenore S. Levine, M.D. (1), Mary Horlick, M.D.

Blurb

Despite dizzyingly fast-paced advances over the past two decades, even the definition of Polycystic Ovarian Syndrome (PCOS) remains in dispute. Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment highlights the recent transition of PCOS from an infertility disorder with a diagnosis based on ovarian tissue histology to a more complex clinical entity, a metabolic disorder in which insulin resistance plays a central role.  With an expert panel of authors, each chapter provides an up-to-date and balanced overview of PCOS, paying special attention to the central role of insulin resistance in the syndrome’s pathogenesis and in the management of its reproductive and metabolic abnormalities.

Comprehensive and thought-provoking, Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment is an invaluable resource for endocrinologists, gynecologists, and internists eager to learn more about this controversial and challenging disease.