`... the present volume offers a wealth of detailed information of great interest to pathologists to be used in basic research as well as in his clinical activities.'
A. Aspects of the primary tumor.- 1. Stroma, generally a non-neoplastic structure of the tumor.- 2. Malignant transformation.- 3. Metabolic changes in malignancy.- 4. Ion deregulation, cell injury, and tumor promotion.- 5. Multiple primary neoplasms: role of autopsy. Selected sites with emphasis on Japan.- 6. Multiple primary neoplasms.- B. Shared aspects of primary and secondary tumors.- 7. Mechanisms of cancer invasion and metastases.- 8. Extracellular matrix and its enzymatic degradation in tumor invasion.- 9. Cell surface and secondary tumor formation.- 10. DNA transfection, genetic instability, and metastasis.- 11. The contribution of DNA methylation to the generation of tumor cell heterogeneity, tumor progression and metastasis.- 12. Neoplastic progression by somatic cell fusion.- 13. Cell junctional alterations in cancer.- 14. Cytogenetic studies in neoplasia (human and animal): Implications, prognosis, and treatment.- 15. Cancer cachexia.- 16. Paraneoplastic syndromes.- Index of subjects.