Introduction Craig S. Niederberger, Dolores J. Lamb, Larry I. Lipshultz and Stuart S. Howards; Part I. Scientific Foundations of Male Infertility: 1. Anatomy and embryology of the male reproductive tract and gonadal development, the epididymis and accessory sex organs Jeffrey T. White, Marisol O'Neill and Meade Haller; 2. Cellular architecture and function of the testis C. Yan Cheng; 3. Maturation and function of sperm Barry T. Hinton; 4. The male reproductive endocrine system Ettore Caroppo; 5. Erection, emission, and ejaculation Ramy Abou Ghayda and Martin N. Kathrins; 6. Genomics, epigenetics and male reproduction Millissia Ben Maamar and Michael Skinner; Part II. Clinical Evaluation of the Infertile Male: 7. Infertility as a metric of men's health Jeremy T. Choy and Michael L. Eisenberg; 8. Ambulatory evaluation of the subfertile male Mark Sigman and Gabriella Avellino; 9. Evaluation of the infertile male's partner Sahar Werthemier, Jessica L. Chen and Margareta D. Pisarska; 10. Imaging the male reproductive system Roger K. Khouri and Tolulope Bakare; 11. The environment and male fertility Rebecca Z. Sokol; 12. Endocrine causes of male infertility: diagnosis and treatment Fiona Yuen, Ronald S. Swerdloff and Christina C. L. Wang; 13. Spermatogenesis: diagnosis of normal and abnormal states Mahmoud Mima and Richard A. Schoor; 14. Inheritance and male fertility Robert D. Oates and Cori Tanrikut; 15. The varicocele Sarah C. Krzastek, Ryan P. Smith and Stuart S. Howards; 16. Infection, inflammation, and immunological causes of male infertility Robert E. Brannigan; Part III. Laboratory Diagnosis of Male Infertility: 17. The Laboratory Evaluation of the Infertile Male J. Scott Gabrielsen; 18. Advanced diagnostic approaches to male infertility Dolores J. Lamb; 19. Evaluating defects in sperm function Christopher J. De Jonge; 20. Cryopreservation of sperm and testis tissue Cappy M. Rothman and Mitchel C. Schiewe; Part IV. Treatment of Male Infertility: 21. Medical treatment of male infertility Craig S. Niederberger, Rodrigo Lessi Pagani and Samuel J. Ohlander; 22. Surgery to improve sperm delivery Saneal Rajanahally, Larry I. Lipshultz and Alex W. Pastuszak; 23. Surgical sperm extraction Peter N. Schlegel; 24. The use of sperm in assisted reproductive technology Gail S. Prins; 25. Male oncofertility Darshan P. Patel, Alexander W. Pastuszak and James M. Hotaling; 26. Male contraception Darius Devlin and Martin M. Matzuk; 27. Future directions in male infertility Ranjith Ramasamy and Premal Patel; Part V. Healthcare Systems and Culture: 28. Mental health and male reproduction William D. Petok; 29. Legal issues and male reproduction Heather E. Ross; 30. Gender affirmation, transgender, and male reproduction Brooke A. Harnisch and Stanton C. Honig; 31. Global and cultural aspects of male reproductive care William J. Huang; Index.