Indwelling Neural Implants: Strategies for Contending with the in Vivo Environment

ISBN-13: 9780367387938 / Angielski / Miękka / 2019 / 296 str.

William M. Reichert

Opis

A compendium of contributions from noted experts in neuroprosthetics and tissue repair, this book addresses the impact, characterization, and mitigation of the healing of tissues that surround an implant. It describes the differences among wound healing in the CNS, PNS, subcutaneous tissue, and bone. It also examines performance issues of implanted neuroprosthetics arising from the chemical, mechanical, thermal, and electrical impact on surrounding tissue. Contributions present both in vitro and in vivo approaches to assessing wound healing response to materials and describe molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between electrode and surrounding tissue. 

Spis treści

Overview of Wound Healing in Different Tissue Types. Considerations for Chronically Implanted Electrodes for Brain Interfacing. Thermal Considerations for the Design of an Implanted Cortical Brain–Machine Interface. In Vitro Models for Neuroelectrodes: A Paradigm for Studying Tissue–Materials Interactions in the Brain. In Vivo Solute Diffusivity in Brain Tissue Surrounding Indwelling Neural Implants. A Molecular Perspective on Understanding and Modulating the Performance of Chronic Central Nervous System (CNS) Recording Electrodes. Soft, Fuzzy, and Bioactive Conducting Polymers for Improving the Chronic Performance of Neural Prosthetic Devices. Strategies for Regeneration and Repair in the Injured Central Nervous System.

O autorze

William M. Reichert