In silico ADME and Pharmacodynamic screening methods in stroke

ISBN-13: 9783659768118 / Angielski / Miękka / 2018 / 120 str.

Kannan Vadivel; Sitty Manohar Babu; Periyannan Muthusamy

Opis

In silico approaches mainly focuses on the selection of the best molecule(s) to synthetize, purchase, or promote at a further stage of a drug discovery process by fast screening methods. In silico study indicates that the selected compounds secured good docking score so they may be pharmacologically active, absorb orally as they obey Lipinski's rule of five and they would be a safe and drug like compound. The future prospect would be the selected ligands to be synthesized and studied for in silico and in vitro / in vivo correlations.

O autorze

Vadivel, Kannan
K. Vadivel M. Pharm, (Ph. D), has completed his U.G from The Tamil Nadu Dr. M.G.R Medical University, Chennai and P.G in Annamalai University, and Ph. D in pharmaceutical sciences (Pharmacology) from JNTUK. He is working as Associate professor in the department of pharmacology, Southern institute of medical sciences, Guntur, last nine years.