In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development

ISBN-13: 9781138725829 / Angielski / Twarda / 2017 / 105 str.

Dhanya Sunil; Pooja R. Kamath; Raghu Chandrashekhar H.

Opis

This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials.

In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates in a wide category of anticancer assays demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules. The major emphasis of the book is to present those bioassays which can be readily set up and practiced in any laboratory with limited funds, facilities or technical know-how.

O autorze

Dhanya Sunil, Ph.D. is an Associate Professor at the Department of Chemistry, Manipal Institute of Technology (MIT), Karnataka, India. She has nine years of research and teaching experience in the field of organic synthesis, medicinal chemistry and anticancer drug development. She has more than thirty journal publications to her credit and has won several best paper awards in conferences both within India and abroad. She is also a recipient of Best Teacher Award from MIT, India. She is a reviewer for reputed journals, such as MedChemComm, Current Drug Metabolism.

Pooja. R. Kamath is persuing her final year Ph.D. in Medicinal Chemistry under the guidance of Dr. Dhanya Sunil at the Manipal Institute of Technology (MIT), India. She has completed her post-graduation in chemistry from the National Institute of Technology, Karnataka and worked on a project at Syngene International Limited. She has six research publications to her credit.

Dr. Raghu Chandrashekhar is an Associate Professor at the Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal. His qualifications include Doctor of Philosophy (PhD). 2007. Dr.MGR Medical University, Chennai, Tamilnadu. M Pharm. 2000-02. Dr.MGR Medical University, Chennai, Tamilnadu - First Class B Pharm. 1992-96. Kuvempu University, Karnataka – Tenth Rank.