Immunotherapy of Renal Cell Carcinoma: Clinical and Experimental Developments

ISBN-13: 9783540528357 / Angielski / Miękka / 1991 / 141 str.

Frans M. J. Debruyne; Ronald M. Bukowski; J. Edson Pontes

Opis

Advanced renal cell carcinoma is resistant to nearly all forms of systematic therapy. For this reason the last decade has seen numerous research groups working on immunotherapeutic strategies. Immunotherapy of Renal Cell Carcinoma reports the contributions of most of the world's leading research groups to two international conferences on the immunobiology of this illness.

Spis treści

Experimental Data.- Considerations in Immunotherapy of Genitourinary Neoplasia.- Murine Renal Cancer (Renca) Model: Background and Preclinical Studies.- Renal Cell Carcinoma: Experimental Metastases.- Oncogenes in Renal Cell Carcinoma.- Molecular Basis and Clinical Relevance of MDR1 Gene Expression in Renal Cell Carcinoma.- Radioimmunoconjugates in Renal Cell Carcinoma.- Interferon and Tumor Necrosis Factor in Renal Cell Carcinoma Model Systems.- Clinical Experience with Biological Response Modifiers in Renal Cell Carcinoma.- Rationale for Immunotherapy in Renal Cell Carcinoma.- Treatment of Renal Cell Carcinoma with Interferon.- Combination Therapy with Interferon in Renal Cell Carcinoma.- Recombinant Interferon Alpha Plus Vinblastine in Metastatic Renal Cell Cancer: Updated Results.- Monotherapy and Combination Therapy with Interferon-?, Interferon-?, and Tumor Necrosis Factor-? in Metastatic Renal Cell Carcinoma.- Treatment of Advanced Renal Cell Carcinoma by Systemic Low-Dose Recombinant Interleukin-2.- Direct Lymphatic Immunotherapy for Metastatic Renal Cell Carcinoma.- Combination Therapy of Renal Cell Carcinoma with Interleukin-2 and Interferon Alpha: The Cleveland Clinic Experience.- Tumor Infiltrating Lymphocytes in Human Renal Cell Carcinoma: Adoptive Immunotherapy and Characterization of Interleukin-2 Expanded Tumor-Infiltrating Lymphocytes.- Active Specific Immunotherapy in Renal Cell Carcinoma: Optimization.