Immunopathology, Diagnosis and Treatment of Hpv Induced Malignancies

ISBN-13: 9780323917971 / Angielski / Miękka / 2022

Prashant Khare; Ashish Jain

Spis treści

1. An overview of HPV: cause, symptoms and clinical manifestation
2. Pathogenesis and immune response against HPV infection
3. Malignancies associated with HPV infection
4. Immunological aspects of HPV/HIV co-infection and risk of gynaecological diseases
5. Cervico-vaginal microbiota and HPV induced cervical cancer
6. Current diagnostic tools for HPV
7. Animal models for the discovery of therapeutic and prophylactic measures against HPV induced malignancies
8. Potential drug targets against HPV and repurposing of existing drugs
9. Recent advances and strategies in vaccine development against HPV
10. Available immunotherapies and future opportunities to prevent HPV-associated cancers

O autorze

Dr. Prashant Khare is Director (R&D) at Center for Advanced Biotechnology Research, Absolute Foods, Gurugram (Haryana), India. Previously he was Ramalingaswami Fellow and Scientist D at Department of Microbiology, All India Institute of Medical Sciences Bhopal, Bhopal (Madhya Pradesh), India. He completed his PhD from Division of Parasitology, Central Drug research Institute, Lucknow, (Uttar Pradesh) India. He has five years of post-doctoral experience from Baylor Institute for Immunology Research and UT Southwestern Medical Center, Dallas, Texas, USA with more than 15 years of research experience in the field of infectious biology, immunology, vaccine and drug development and inflammation and associated cancer. He has published more than 30 research papers in highly reputed international journals such as Nature Immunology and Nature communication. He has reviewed publications for various international journals and served as editorial role in well reputed journals. Presently he is working to identify novel drug molecules against infectious cancer. Dr. Ashish Jain is working as an Assistant Professor (senior scale) since last eleven years in the Department of Microbiology, Smt. CHM College Ulhasnagar; affiliated with the University of Mumbai (Maharashtra), India. He has completed his PhD from Division of Endocrinology, Central Drug Research Institute, Lucknow (Uttar Pradesh) India on spermicides and anti-Trichomonas molecules and their mode of action. He has published more than 20 reputed international research papers and reference books in the field of Sexually transmitted infections and reproductive biology and credited international patents in his account. He is a recognized postgraduate teacher and PhD guide of University of Mumbai in Microbiology subject. Presently he is working to investigate the role of vaginal microbiota on reproductive health.