Immunology and Its Impact on Infections in Surgery

ISBN-13: 9783540581451 / Angielski / Miękka / 1994 / 253 str.

Rainer Engemann; Rene Holzheimer; A. Thiede

Opis

Presents recent developments in immunology and the impact of the treatment of infections in critical care and surgery. The impact of a standard treatment such as antibiotic therapy is evaluated and possible future therapy modalities are outlined.

Spis treści

Animal Models.- Yersinia enterocolitica Infection in Mice: A Possible Experimental Model for the Immunobiology of Gram-Negative Infections.- Development of a New Animal Model for Chronic Abscess-Forming Peritonitis.- Tolerance to Endotoxin in an Animal Model of Acute Pancreatitis Is Associated with Improved Cellular Immune Function.- Prolonged and Recurrent Endotoxemia in Domestic Pigs: A First Step Toward a Porcine Model of Human Multiple Organ Failure?.- Endotoxin, Interferon-?, Biopterin, Serum Phospholipase A2 Activity, and ?-Endorphin as Differentiation Factors and Their Correlations in the Acute Immune Response During Lethal Gram-Negative Sepsis in LEW Rats.- Gene Expression.- The Effects of Burn Injury on Cytokine Production and Gene Expression.- Genomic Fingerprinting for the Evaluation of Epidemic Processes.- Interleukin-2 Receptor Expression Is Unaffected by Thermal Injury.- Keratinocytes Express an Intracellular Marker Gene and Regenerate the Epidermis in Porcine Full-Thickness Wounds After Retroviral Gene Transfer.- The Influence of Non-specific Inflammatory and Immunological Reactions on the Expression of Major Histocompatibility Complex and Activation Antigens After Murine Hepatic Transplantation.- Cellular Activation (1).- Cellular Endothelial Interaction and the Activation of Plasma Cascade Systems in Sepsis.- The Role of the Macrophage in Early Post-traumatic Immunosuppression.- Role and Measurement of Endotoxin in Septic Shock.- Normal Human Immune Peritoneal Cells: Predominance of Memory Lymphocytes.- Supplementation of Postoperative Enteral Nutrition with Arginine, RNA, and Omega-3 Fatty Acids Increases the Activity of Blood Monocytes in Cancer Patients.- Mild Surgery-Induced Changes in Human Peripheral Blood Lymphocytes.- Cell Activation (2).- Tissue Perfusion and Oxygenation Related to Wound Healing and Resistance to Infection.- Cell Cycle Progression and Signal Transduction in Normal and IgM Transgenic B Cells.- Pit Cells: Some Observations on Their Ultrastructure in Patients with Carcinoma and Viral Hepatitis Compared with Pit Cells in Rats Treated with Biological Reponse Modifiers.- Mediators.- The Polymorphonuclear Neutrophil: A Newly Recognized Participant in the Immune Response.- IL-6 Changes After Surgical Stress.- Does Epidural Analgesia During Labor Alter Postpartum Maternal IL-6 Serum Levels?.- The Effect of Epidural Analgesia During Labor on the Immune System. Part 2. Neonatal Blood IL-6 Levels.- Risk Factors.- Risk Factors for the Development of Surgical Infection.- Anergy and Postoperative Septic Complications.- The Relationship Between Platelet, Lymphocyte and Monocyte Counts, Sepsis and Survival in Polytrauma Patients.- CD4+ Lymphocytes as a Prognostic Indicator of Surgical Infection in the Immunodepressed Patient.- Immunologic Monitoring in Patients with Glioma Treated Neurosurgically.- Therapy Modalities (1).- High-Dose Immunoglobulins for Prophylaxis of Severe Sepsis.- Perioperative Immunity, Inflammatory Response, and Postoperative Infection in Cardiopulmonary Bypass Patients.- Therapy Modalities (2).- Immunological Consequences of Antibiotic Therapy.- Immunomodulation in the Critically Ill Surgical Patient.- Effect of Clindamycin in a New Standardized Animal Model for Chronic Abscess-Forming Peritonitis.- GM-CSF Modulates Immune Function and Improves Survival After Thermal Injury.- Early-Phase Endotoxin Tolerance Enhances Survival in a Porcine Endotoxin Shock Model.

O autorze

The book covers recent developments in immunology and the impact on the clinical treatment of infections in surgery. World-renowned scientists and clinicians have contributed papers on animal models, gene expression, cellular activation, mediators, risk factors, and therapy modalities.