Immune Responses to Biosurfaces: Mechanisms and Therapeutic Interventions

ISBN-13: 9783319372778 / Angielski / Miękka / 2016 / 242 str.

John D. Lambris; Kristina N. Ekdahl; Daniel Ricklin

Spis treści

Part 1. Mechanisms.- Thromboinflammation in Therapeutic Medicine.- Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions.- Role of Complement on Broken Surfaces after Trauma.- Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches.- Part 2. Biomaterials.- The Lectin Pathway of Complement and Biocompatibility.- Foreign Body Reaction to Subcutaneous Implants.- Molecular Characterization of Macrophage-Biomaterial Interactions.- Heparan Sulfate Proteoglycan Metabolism and the Fate of Grafted Tissues.- Part 3. Transplantation.- Xenotransplantation of Cells, Tissues, Organs and the German Research Foundation Transregio Collaborative Research Centre 127.- Macro encapsulated Pig Islets Correct Induced Diabetes in Primates up to 6 Months.- Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantation—Points for Therapeutic Interventions.- Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy.- Complement Interception Across Humoral Incompatibility in Solid Organ Transplantation–A Clinical Perspective.