1. Introduction 2. Molecular profiling and mutational landscape of pancreatic cancer 3. Tumor microenvironment and immune components interaction in pancreatic ductal adenocarcinoma 4. Identification of immune targeted molecules in pancreatic ductal adenocarcinoma 5. Targeting macrophages for pancreatic cancer therapy 6. Targeting cancer-associated fibroblasts in pancreatic ductal adenocarcinoma 7. Targeting short-lived immunosuppressive myeloid cells for PDAC therapy 8. Targeting T-regs in PDAC 9. Immune-modulators for PDAC therapy 10. Current clinical trials in PDAC immunotherapy 11. Precision medicine in PDAC immunotherapy 12. Artificial intelligence in pancreatic cancer immunotherapy