Image-Guided High-Precision Radiotherapy

ISBN-13: 9783031086007 / Angielski / Twarda / 2022 / 314 str.

Esther G. C. Troost

Opis

This book equips readers with detailed knowledge on the current status of image-guided radiotherapy with photons and particles and highlights issues that need to be addressed in order to further improve treatment outcomes. The opening chapters cover clinical and technical aspects of target volume definition using anatomic (computed tomography and magnetic resonance imaging; MRI) as well as functional (MRI and positron emission tomography) imaging. Up-to-date information is then provided on the full range of image-guided high-precision radiotherapy techniques, including IMRT/VMAT, stereotactic body radiation therapy, MR-guided linear accelerators, MR-guided brachytherapy, and particle therapy. The role of ultrasonography in image-guided radiotherapy is discussed, as are the available means for target volume demarcation and stabilization and adaptive radiation therapy. Finally, outcome evaluation is explored in depth, with a particular focus on the role of multimodality imaging in predicting tumor control and normal tissue toxicity. The authors are experts in different specialties and the book will be of high value for radiation oncologists, medical physicists, radiologists, nuclear medicine physicians, and radiation technicians.

Spis treści

PART I: Target volume definition

1.       Use of FDG-PET for target volume definition in radiotherapy

2.       Definition of the biological target volume based on PET (lung, rectum, brain)

3.       Use of anatomical and functional MRI in radiation treatment planning

 

PART II: Image-guided RT techniques

4.       Introduction in available in-room equipment for online positioning

5.       IMRT/VMAT, SABR

6.       MR-integrated linear accelerators – concepts

7.       MR-integrated linear accelerators – first clinical results

8.       MR-guided brachytherapy

9.   Ultrasonography in image-guided radiotherapy – current status and future challenges

10.   Image-guided particle therapy

11.   Means for target volume demarcation and stabilisation (fiducial markers, balloons, spaceOR)

12.   Adaptive radiation therapy

13. AI for image-guided radiotherapy

 

PART III: Outcome evaluation

14.   Multimodality imaging for prediction of tumour control following radiotherapy

15.  Modelling for radiation treatment outcome

O autorze

Esther Troost, MD, PhD, is a radiation oncologist, chair of the Department of Radiotherapy and Radiation Oncology of the University Hospital Carl Gustav Carus, professor of image-guided high-precision radiation therapy at the Faculty of Medicine of the Technische Universität Dresden, Germany, and group leader at the Helmholtz-Zentrum Dresden-Rossendorf, Germany. She focuses on incorporating anatomical and functional imaging in radiation treatment planning and early response evaluation for personalised treatment and on exploiting imaging changes as objective measures of tumor response. Professor Troost is a reviewer for numerous international scientific journals, a member of national and international societies, and director of the European Society for Radiotherapy and Oncology (ESTRO) teaching course on “Target volume delineation”.