Igg4-Related Kidney Disease

ISBN-13: 9784431566762 / Angielski / Miękka / 2018 / 311 str.

Saito, Takao

Opis

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

Spis treści

Part I. General Remarks.-

1. IgG4-Related Disease: History and Overview.-

2. IgG4-Related Disease: Pathological Features and Differential Diagnosis.-

3. Potential Pathways in The Pathogenesis of IgG4-Related Disease.- 

4. Does IgG4-Related Disease Have an Autoimmune Basis?.-

5. Plasmablasts: A Promising Biomarker in IgG4-RD.-

Part II. Features of IgG4-Related Ridney Disease and Associated Conditions.-

6. Overview of IgG4-Related Kidney Disease.-

7. IgG4-Related Kidney Disease: Clinical and Laboratory Features.-

8. Imaging Findings.- 

9. Characteristic Tubulointerstitial Nephritis in IgG4-Related Kidney Disease.-

10. Electron Microscopic Findings.-

11. IgG4-RelatedKidney Disease: Pathological Features –Membranous Glomerulonephritis.-

12. IgG4-RelatedKidney Disease: Pathological Features –Other Glomerular Disease.-

13. IgG4-Related kKidney Diseases and Conditions: Renal Pelvic and Ureteral Diseases.-

O autorze

Takao Saito, Emeritus Professor, Faculty of Medicine, Fukuoka University

John H. Stone, Massachusetts General Hospital 

Hitoshi Nakashima, Division of Nephrology & Rheumatology, Department of Internal Medicine, Fukuoka University 

Takako Saeki, Department of Internal Medicine, Nagaoka Red Cross Hospital 

Mitsuhiro Kawano, Division of Rheumatology, Department of Internal Medicine, Kanazawa University