Igg4-Related Kidney Disease

ISBN-13: 9784431556862 / Angielski / Twarda / 2016 / 311 str.

Takao Saito; John H. Stone; Hitoshi Nakashima

Opis

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4RKD). IgG4-related disease (IgG4RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4RD have been reported and are recently attracting attention as IgG4RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

Spis treści

Part I. General Remarks.-

1. IgG4-Related Disease: History and Overview.-

2. IgG4-Related Disease: Pathological Features and Differential Diagnosis.-

3. Potential Pathways in The Pathogenesis of IgG4-Related Disease.- 

4. Does IgG4-Related Disease Have an Autoimmune Basis?.-

5. Plasmablasts: A Promising Biomarker in IgG4-RD.-

Part II. Features of IgG4-Related Ridney Disease and Associated Conditions.-

6. Overview of IgG4-Related Kidney Disease.-

7. IgG4-Related Kidney Disease: Clinical and Laboratory Features.-

8. Imaging Findings.- 

9. Characteristic Tubulointerstitial Nephritis in IgG4-Related Kidney Disease.-

10. Electron Microscopic Findings.-

11. IgG4-RelatedKidney Disease: Pathological Features –Membranous Glomerulonephritis.-

12. IgG4-RelatedKidney Disease: Pathological Features –Other Glomerular Disease.-

13. IgG4-Related kKidney Diseases and Conditions: Renal Pelvic and Ureteral Diseases.-

O autorze

Takao Saito, Emeritus Professor, Faculty of Medicine, Fukuoka University

John H. Stone, Massachusetts General Hospital 

Hitoshi Nakashima, Division of Nephrology & Rheumatology, Department of Internal Medicine, Fukuoka University 

Takako Saeki, Department of Internal Medicine, Nagaoka Red Cross Hospital 

Mitsuhiro Kawano, Division of Rheumatology, Department of Internal Medicine, Kanazawa University