IDENTIFICATION AND CHARACTERIZATION OF NOVEL NATURAL NF- B INHIBITORS

ISBN-13: 9786209360435 / Angielski / Miękka / 2025 / 92 str.

Muhammad Ishaq

Opis

Nuclear factor- B (NF- B) depict a family of transcription factors, which modulate collection of genes associated with inflammatory and immune responses. Inevitable NF- B activation involve pathogenic process of various diseases like inflammation and cancer. NF- B signaling in cancer cells is involved in cellular proliferation, angiogenesis, invasion, metastasis, development of drug resistance and anti-apoptosis. The present study was aimed to identify potent NF-kB inhibitors using molecular docking study.