Hypoxia: Through the Lifecycle

ISBN-13: 9780306480720 / Angielski / Twarda / 2003 / 372 str.

Robert C. Roach; Peter D. Wagner; Peter H. Hackett

Opis

The International Hypoxia Symposium convenes biannually to bring together international experts from many fields to explore the state of the art in normal and pathophysiological responses to hypoxia. Representatives from five continents and 32 countries joined together in February 2003 for four days in the dramatic mountains of Banff, Alberta. As editors of the Proceedings of the International Hypoxia Symposia, we strive to maintain a 26 six year tradition of presenting a stimulating blend of clinical and basic science papers focused on hypoxia. Topics covered in 2003 include hibernation and hypoxia, hypoxia and fetal development and new advances in high altitude pathophysiology, oxidative stress and membrane damage, hypoxic regulation of blood flow, heat shock proteins in hypoxia, and future directions in hypoxia research. In 2003 we also had the privilege ofhonoring John W. Severinghaus as a friend, colleague, mentor and inspiration to many in the field. Tom Hornbein's personal tribute to John Severinghaus is the first chapter in this volume, followed by an entertaining update of the history of the discovery of oxygen written by John Severinghaus.

Spis treści

Hypoxia Honoree.- 1. A Tribute to John Wendell Severinghaus.- 2. Fire-Air and Dephlogistication.- Hibernation And Hypoxia.- 3. Mammalian Hibernation.- 4. Oxygen Conformance of Cellular Respiration.- Newadvances Oxygen Sensing.- 5. Current Paradigms in Cellular Oxygen Sensing.- 6. Why Is Erythropoietin Made in the Kidney?.- 7. Hypoxia and High Altitude.- Hypoxia: An Essential For A Healthy Fetus.- 8. Hypoxia and Lung Branching Morphogenesis.- 9. Hypoxia and Lung Branching Morphogenesis.- 10. Hypoxic Induction of Myocardial Vascularization During Development.- Newadvances: High Altitude Pathophysiology.- 11. Role of Cerebral Blood Volume in Acute Mountain Sickness.- 12. Ventilation, Autonomic Function, Sleep and Erythropoietin.- 13. A Tribute to John Wendell Severinghaus.- Oxidative Stress And Membrane Damage.- 14. Oxidative Stress and Aging.- 15. Radical Dioxygen.- Hypoxic Regulation Of Blood Flow In Humans.- 16. Skeletal Muscle Circulation and the Role of Epinephrine.- 17. ?-Adrenergic Receptors and Functional Sympatholysis in Skeletal Muscle.- 18. Skin Blood Flow and Temperature Regulation.- Heat Shock Proteins In The Lungs.- 19. Turning up the Heat in the Lungs.- 20. Proteins Involved in Salvage ofthe Myocardium.- Future Directions: Hypoxia Research.- 21. The NO ? K+ Channel Axis in Pulmonary Arterial Hypertension.- 22. Non-Erythroid Functions of Erythropoietin.- Special Tribute.- 23. Peter Hochachka and Oxygen.- Epidemiology Of Altitude Illness.- 24. Proposal for Scoring Severity in Chronic Mountain Sickness (CMS).- 25. Epidemiological Modeling ofAcute Mountain Sickness (AMS).- Late Abstracts.- 26. Abstracts Submitted Late to 13th International Hypoxia Symposium.- Author Index.