Hypercalcemia: Clinical Diagnosis and Management

ISBN-13: 9783030931810 / Angielski / Twarda / 2022

Walker, Marcella Donovan

Opis

While there are some books that include discussions of individual causes of hypercalcemia, there are none that provide basic guidance on the approach, diagnosis and treatment of hypercalcemia, while also offering an in-depth, detailed, state-of-the-art review of the individual causes by world-renowned experts in the field. 

Topics discussed include pathophysiology, differing diagnostic strategies for both the pediatric and adult patient, the various forms and causes of hypercalcemia as well as current treatment regimens and algorithms. Selected chapters are enhanced with illustrative cases, thereby complementing theoretical matter with real-world applications to the practice of medicine, and tables and figures allow the reader to solidify concepts in an easily digestible format. 

By integrating an evidence- and guideline-based framework along with an up-to-date, research-based summary of each cause, Hypercalcemia is relevant for expert clinicians and up-and-coming medical students alike. 

Spis treści

Normal Regulation of Serum Calcium

Pathophysiology and Clinical Manifestations of Hypercalcemia

Diagnostic Approach to the Adult Patient with Hypercalcemia

Diagnostic Approach and Treatment of the Pediatric Patient with Hypercalcemia

Primary Hyperparathyroidism

Genetic Causes of Hypercalcemia/Primary Hyperparathyroidism

Familial Hypocalciuric Hypercalcemia and Disorders of the Calcium Sensing Receptor

Overview of Hypercalcemia of Malignancy

Humoral Hypercalcemia of Malignancy/PTHRP

Hypercalcemia Related to Osteolytic Metastases and Myeloma

Hypercalcemia Due to Malignancy Related Production of 1,25 (OH)2

Vitamin D Intoxication

Benign 1,25(OH)2 Vitamin D-Mediated Hypercalcemia

Medication-Induced Hypercalcemia

Non-Parathyroid Hormone Mediated Endocrine Causes of Hypercalcemia

Rare and Other Causes of Hypercalcemia

O autorze

Marcella Donovan Walker, MD, New York-Presbyterian Hospital, Columbia University Irving Medical Center, Division of Endocrinology, New York, NY, USA