Hydroxamic Acids: A Unique Family of Chemicals with Multiple Biological Activities

ISBN-13: 9783662511039 / Angielski / Miękka / 2016 / 312 str.

Satya P. Gupta

Opis

This book provides comprehensive coverage of the compound class of Hydroxamic Acids, which possess a wide spectrum of biological activities. These are of interest to theoretical and experimental chemists for their potential use in drug design and development.

Spis treści

Chemistry of Hydroxamic Acids.- Theoretical Studies on Hydroxamic Acids.- Hydroxamic Acids as Carbonic Anhydrase Inhibitors.- Structure-Activity Relationships of Hydroxamic Acids as Matrix Metalloproteinase Inhibitors.- Hydroxamic Acid Derivatives as Anticancer Agents.- Hydroxamic Acids as Histone Deacetylase Inhibitors.- Quantitative Structure-Activity Relationship Studies on Hydroxamic Acids Acting as Histone Deacetylase Inhibitors.- Hydroxamic Acids as Carbonucleotide Reductase Inhibitors.- Hydroxamic Acids as Inhibitors of Urease in the Treatment of Helicobacter pylori Infections.- Therapeutic Potential of Hydroxamic Acids for Microbial Diseases.- Hydroxamic Acids as Chelating Mineral Collectors.

O autorze

Satya P. Gupta is Professor of Eminence in the Department of Applied Sciences at Meerut Institute of Engineering and Technology (MIET), Meerut. He has a wide range of experience in publishing including acting as a Guest Editor of Current Medicinal Chemistry and Combinatorial Chemistry & High Throughput Screening and serving as Editor-in-Chief for several journals. Additionally, he has guest-edited two volumes of Topics in Heterocyclic Chemistry and recently edited a number of books. Dr. Gupta has also served on the Editorial Board of the Indian Journal of Chemistry, Sec B (CSIR, New Delhi) and presently is at the editorial board of Letters in Drug Design and Discovery, Online Journal of Organic Chemistry, and BenSci Journal, and Research and Reports in Medicinal Chemistry. Dr. Gupta has contributed more than a half dozen reviews in Chemical Reviews in addition to many in Progress in Drug Research, Current Medicinal Chemistry, and some others, besides hundreds of excellent original publications in various internationally reputed journals.

Blurb

Satya P. Gupta's Hydroxamics Acids is the first book to compile invited articles written by international experts on the class of compounds hydroxamic acids. Found to possess a wide spectrum of biological activities, the hydroxamic acids are of interest for  theoretical and experimental chemists who can study and make use of them in drug design and development. Chapters in this book provide a diverse and comprehensive coverage of this compound class and consequently this publication is a valuable resource for researchers in chemical, pharmaceutical and biological sciences.