Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes

ISBN-13: 9783030179434 / Angielski / Miękka / 2020 / 326 str.

Jan Tachezy

Spis treści

Introduction, history etc.., Miklos Müller, The Rockefeller University, USA,- Anaerobic Eukaryotes in Persuit Normality: the Eolution of mitochondria-derived organelle, William Martin, Germany,- Protein Import into Hydrogenosomes and Mitosomes, Abhijith Radhakrishna Makki, Jan Tachezy, Pavel Doležal,- Structure of the Hydrogenosome (morphogenesis, electron microscopy, comparison of various hydrogenosomes..), Marlene Benchimol, Brasil,- Hydrogenosomes of anaerobic ciliates, Johannes H.P. Hackstein, The Netherlands,- Metabolism of trichomonad hydrogenosomes (energy metabolism, electron transport…), Ivan Hrdy, Charles University, Czech Republic,- Hydrogenosomes of anaerobic chytrids (Neocallimastix, Piromyces), L. Tielens,  J. Hellemond, F. Voncken, J. Heckstein,- The proteome of T. vaginalis hydrogenosomes, Petr Rada Charles University, Czech Republic,- Mitosomes in parasitic protists: Entamoeba histolytica, Giardia intestinalis, microsporidia…, J. Tachezy, Pavel Doležal,- Remnant mitochondria of Cryptosporidium parvum, Anastasios Tsaousis, UK,- Mitochondrion-derived organelles in free-living protists, A. Roger M. Kolísko,-  Organisms without mitochondria, how it may happen?, V. Hampl.

Blurb

"Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes, 2nd edition" provides a comprehensive summary of the current knowledge on these organelles, which occur in unicellular, often parasitic organisms, including human pathogens. It discusses the discovery of these widely distributed organelles, as well as their evolution and recent advances in the study of their structure and function. The book also describes their properties, such as protein import, structure, metabolism and adaptation, their proteome and their role in drug activation and resistance.

The book will appeal to researchers and students interested in biology and medicine, and to those who are mainly interested in basic science-cell biology, parasitology, microbiology, evolution etc., but also to those interested in organelles as potential targets for chemotherapy.