Human Microbiome in Health, Disease, and Therapy

ISBN-13: 9789819951130 / Angielski

Pallaval Veera Bramhachari

Spis treści

Chapter 1_A scoping review of research on the  unfolding human microbiome landscape in the metagenomics era.- Chapter 2_Elucidating the Role of Gut-Brain-Axis in Neuropsychiatric and Neurological Disorders.- Chapter 3_Role of Gut Microbiome Composition in Shaping Host Immune System Development and Health.- Chapter 4_Understanding the probiotics and mechanism of immunomodulation interactions with the gut-related immune system.- Chapter 5_Antimicrobial agents induced microbiome dysbiosis and its impact on immune system and metabolic health.- Chapter 6_Nutritional Modulation of Gut Microbiota Alleviates metabolic and neurological disorders.- Chapter 7_Hepatocellular carcinoma and human gut microbiome: Association with disease and scope for therapeutic intervention.- Chapter 8_Influence of intestinal Microbiomes on the COVID progression and its effects by the immunotherapeutic modulation.- Chapter 9_The Human Breast Milk Microbiome: Establishment and resilience of microbiota over mother-infant relationship.- Chapter 10_The dynamics of skin microbiome: Association of microbiota with skin disorders and therapeutic interventions.- Chapter 11_Advances in human urinary microbiome: Functional role beyond infections.- Chapter 12_Role of microbiomes in defining the metabolic and regulatory networks that distinguishes between good health and a continuum of disease states.- Chapter 13_The microbiome- antibiotic resistome: Significant strategies towards Microbiome-Targeted therapeutic interventions in medicine.- Chapter 14_New paradigms on Microbiome diagnostics design and engineering.- Chapter 15_Microbiome Therapeutics-Emerging Concepts and Challenges in translational microbiome research.- Chapter 16_Insights on the new generation technologies and capabilities of bioinformatic tools to understand microbiome research and microbial world.

O autorze

Dr. Pallaval Veera Bramhachari is currently an associate professor in the Department of Biotechnology at Krishna University, Machilipatnam, AP, India. He has earlier served as a postdoctoral research scientist at the Bacterial Pathogenesis Laboratory, Queensland Institute of Medical Research (QIMR-Berghofoer Research Center), Brisbane, Australia, and a DBT postdoctoral fellow at the Department of Microbiology and Cell Biology, Indian Institute of Science (IISc), Bangalore. He completed his PhD in Microbiology from Goa University, India. His major research interests are the investigation of applied research in microbiology and cell biology including the biochemical mechanism of bacterial-biofilm formations, extracellular microbial polysaccharides, and the structure-function relationship of bacterial biosurfactants (glycolipids and rhamnolipids), pathogenic and virulence characteristics of bacteria, basic, and translational cancer research. He has published more than 140 research articles in Scopus-indexed journals, authored and co-authored 8 international books and invited book chapters in prestigious peer-reviewed international, and presented 50 abstracts at various national and international conferences. He has served as reviewer and editorial board member for a number of international journals, including Plos, Frontiers, Elsevier, Springer, and John Wiley.

He is a member of numerous international scientific societies and organizations, such as Indian Science Congress and Society of Biological Chemists, India. He completed two major research projects for the SERB, DST NRDMS, and Government of India. He was awarded a Travel Scholarship from QIMR in 2007, Australia, for attending the 4th Indo-Australian Biotechnology Conference in Brisbane, Australia. He was awarded with a Young Scientist Travel Fellowship (2007) from the DST, Government of India, for attending XVII Lancefield International Symposium at Porto Heli, Greece (2008). He was conferred with various prestigious awards: Science Education Research Board (SERB), Government of India Young Scientist Award (2011) with a research project and nominated as Associate Fellow of Andhra Pradesh Academy of Sciences (APAS) (2016), Master Trainer: Andhra Pradesh English Communications Skills Project. British Council and APSCHE (2017), Andhra Pradesh State Best Scientist Award (2017), Dr. V. Ramalingaswamy Memorial Award for Biomedical Sciences (2019), KAPL Award (Industrial Biotechnology), SBTI Annual Award (2022), Dr. APJ Abdul Kalam Teacher Excellence Award (2022). He also obtained two Indian patents in 2017. He has more than 15 years of teaching experience in molecular microbiology, virology and immunology, IPR, bioprocess engineering, and microbial and environmental biotechnology at the university level.

 

 

Blurb

This book illustrates the role of the human microbiome in health and diseases. It discusses the association of an imbalanced human microbiome with different human diseases, including inflammatory, metabolic conditions, neurological, cardiovascular, and respiratory diseases.  The book further reviews the association between intestinal microbiota and immune defense systems. The book provides evolving knowledge of the development, complexity, and functionality of the healthy gut microbiota and covers interventions that modulate and stabilize the gut microbiota. Further, it introduces the human microbiome as a reservoir of AMR genes, the current knowledge on the resistome, and the recent and upcoming advances in molecular diagnostic approaches to unravel this reservoir. Toward the end, the book reviews the advances in understanding the human urinary microbiome and its potential role in urinary tract infection. The chapter also presents the dynamics of the skin microbiome and the association of microbiota with skin disorders and therapeutic interventions. This book is an invaluable read for health professionals, medical students, microbiologists, and scientific research communities who are eager to update themselves with recent trends in microbiome research.