Human Immunodeficiency Virus Type 1 (Hiv-1) and Breastfeeding: Science, Research Advances, and Policy

ISBN-13: 9781493952786 / Angielski / Miękka / 2016 / 315 str.

Athena P. Kourtis; Marc Bulterys

Opis

The HIV pandemic continues to take a heavy toll. With more than 1,000 new pediatric infections daily, mostly mother-to-child transmissions, this book studies research aiming to keep the nutritional and immunological benefits of breast milk for at-risk babies.

Recenzje

From the reviews:

"The purpose is to convey recent information about HIV-1 transmission by breastfeeding, the virology and immunology around breastfeeding ... and the public health implications of policy recommendations and research on HIV-infected women. ... The book is most appropriate for academic researchers and clinicians, but some sections that are summaries of the known data would be relevant for general practitioners and medical residents. ... I would recommend this as an excellent resource for what is known about the field of HIV-1 and breastfeeding." (Natalie M. Neu, Doody's Review Service, September, 2012)

Spis treści

Breastfeeding and transmission of HIV-1: Epidemiology and Global Magnitude.- Breastfeeding and Transmission of viruses other than HIV-1.- Breastfeeding among HIV-1-infected women: Maternal health outcomes and social repercussions.- Virologic determinants of breast milk transmission of HIV-1.- HIV-1 resistance to antiretroviral agents: Relevance to mothers and infants in the breastfeeding setting.- Animal models of HIV transmission through breastfeeding and pediatric HIV infection.- Antiretroviral pharmacology in breast milk.- HIV-1 diagnosis of the breastfed infant.- The immune system of breast milk: antimicrobial and anti-inflammatory properties.- Humoral /mucosal/innate immunity in the breast milk in the context of HIV-1 infection.- Cellular immunity in breast milk: Implications for Postnatal Transmission of HIV-1 to the infant.- Antiretroviral drugs during breastfeeding for the prevention of postnatal transmission of HIV-1.- Immune Approaches for the prevention of breast milk transmission of HIV-1.- Non-antiretroviral approaches to prevention of breast milk transmission of HIV-1: Exclusive breastfeeding, early weaning, treatment of expressed breast milk.- Breast milk micronutrients and mother-to-child transmission of HIV-1.- Historical perspective of African-based research on HIV-1 transmission through breastfeeding: The Malawi experience.- Breastfeeding and HIV infection in China.- The role of the President’s Emergency Plan for AIDS Relief (PEPFAR) in infant and young child feeding guideline development and program implementation.- Should women with HIV-1 infection breastfeed their infants? Balancing the scientific evidence, ethical issues and costs-policy considerations.- HIV-1 and Breastfeeding in the United States.- Epilogue. The future of breastfeeding in the face of HIV-1 infection: Science and Policy.