Human Evolutionary Genetics

ISBN-13: 9780815341482 / Angielski / Miękka / 2013 / 650 str.

Mark Jobling

Opis

Now in full-color, the Second Edition of Human Evolutionary Genetics has been completely revised to cover the rapid advances in the field since publication of the highly regarded First Edition. Written for upper-level undergraduate and graduate students, it is the only textbook to integrate genetic, archaeological, and linguistic perspectives on human evolution, and to offer a genomic perspective, reflecting the shift from studies of specific regions of the genome towards comprehensive genomewide analyses of human genetic diversity. Human Evolutionary Genetics is suitable for courses in Genetics, Evolution, and Anthropology. Those readers with a background in anthropology will find that the streamlined genetic analysis material contained in the Second Edition is more accessible. The new edition also integrates new technologies (including next-generation sequencing and genome-wide SNP typing) and new data analysis methods, including recent data on ancient genomes and their impact on our understanding of human evolution. The book also examines the subject of personal genomics and its implications.

Spis treści

1. An Introduction to Human Evolutionary Genetics
Section I: How Do We Study Genetic Variation?
2. Organization and Inheritance of the Human Genome
3. Human Genome Variation
4. Finding and Assaying Genome Diversity
Section II: How Do We Interpret Genetic Variation?
5. Processes Shaping Diversity
6. Making Inferences from Diversity
Section III: Where and When Did Humans Originate?
7. Humans as Apes
8. What Genetic Changes Have Made Us Human?
9. Origins of Modern Humans
Section IV: How Did Humans Colonize the World?
10. The Distribution of Diversity
11. The Colonization of the Old World And Australia
12. Agricultural Expansions
13. Into New Found Lands
14. What Happens When Populations Meet?
Section V: How Is An Evolutionary Perspective Helpful?
15. Understanding the Past, Present and Future of Phenotypic Variation
16. Evolutionary Insights into Simple Genetic Diseases
17. Evolution and Complex Diseases
18. Identity and Identification