Human Emerging and Re-Emerging Infections

ISBN-13: 9781118644713 / Angielski / Twarda / 2016 / 1088 str.

Sunit Kumar Singh

Opis

Emerging and re-emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time-consuming process due to the -novel- nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology. Human Emerging and Re-emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections. Human Emerging and Re-emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Spis treści

Volume I
List of Contributors ix

Preface xvii

Acknowledgments xix

About the Editor xxi

1 Pathogenesis of the OldWorld Arenaviruses in Humans 1
Igor S. Lukashevich

2 Pathogenesis of New World Arenaviruses in Humans 29
Verónica Martín, Stefan Kunz, Esteban Domingo, and Noemí Sevilla

3 Pathogenesis of Emerging and Novel Bunyaviruses in Humans 43
Cong Jin and Dexin Li

4 Pathogenesis of Rift Valley Fever in Humans 73
Inaia Phoenix and Tetsuro Ikegami

5 Pathogenesis of Hantavirus Infections 95
Tarja Sironen Olli Vapalahti and Alexander Plyusnin

6 Molecular Pathogenesis of Japanese Encephalitis Virus Infection 113
Sunit Kumar Singh

7 Dengue Virus Infection in Humans: Epidemiology Biology Pathogenesis and Clinical Aspects 125
Fatih Anfasa, Leonard Nainggolan, and Byron E. E. Martina

8 Pathogenesis of West Nile Virus in Humans 145
Rianna Vandergaast, Katherine L. Hussmann, and Brenda L. Fredericksen

9 Overview on Chikungunya Virus Pathogenesis 177
Sunit Kumar Singh

10 Nipah Virus Infections in Humans 189
Kaw Bing Chua, Chong Tin Tan, and Kum Thong Wong

11 Pathogenesis of Hendra Virus in Humans 207
Chad E. Mire, Benjamin A. Satterfield, and Thomas W. Geisbert

12 Pathogenesis of Rotavirus in Humans 227
Carlos Fernando Narváez, Martha C. Mesa, Alfonso Barreto, Luz–Stella Rodríguez, and Juana Angel

13 Pathogenesis of Papillomaviruses in Humans 243
John Doorbar

14 Kaposi′s Sarcoma Associated Herpesvirus Pathogenesis 265
Lia R. Walker, Anshul V. Subramanya, Zeal T. Akula, and Shaw M. Akula

15 Microsporidiosis in Humans 281
Henry Shikani, Elizabeth S. Didier, and Louis M. Weiss

16 Pathogenesis of Toxoplasma gondii in Humans 303
Hong–Juan Peng, Feng Tan, and David S. Lindsay

17 Pathogenesis of Human African Trypanosomiasis 319
Jennifer Cnops and Stefan Magez

18 Pathogenesis of Leishmaniasis in Humans 337
Steve Oghumu, Gayathri Natarajan, and Abhay R. Satoskar

19 Pathogenesis of Chagas Disease in Humans 349
María–Jesús Pinazo, Faustino Torrico, and Joaquim Gascón

20 Pathogenesis of Cryptosporidium in Humans 371
Gabriela Certad, Marwan Osman, and Sadia Benamrouz

21 Pathogenesis of Malarial Parasites in Humans 393
Caroline Lin Lin Chua, Ricardo Ataíde, Alexandra J. Umbers, and Phillipe Boeuf

22 Pathogenesis of Trichomonas vaginalis in Humans 423
Marlene Benchimol, Antonio Pereira–Neves, and Wanderley de Souza

23 Loa loa Pathogenesis in Humans 441
Akue Jean Paul

24 Nematode LarvaMigrans 453
Kumara Singaravelu, Christina M. Coyle, Yuri C. Martins, Louis M. Weiss, Fabiana S. Machado,
Herbert B. Tanowitz, and Kevin R. Kazacos

25 Pathogenesis of Human Schistosomiasis 481
Thien–Linh Le, Susanne H. Sokolow, Olfat Hammam, Chi–Ling Fu, and Michael Hsieh

26 Vector–Borne Parasitic Zoonotic Infections in Humans 505
Domenico Otranto and Filipe Dantas–Torres

Index i1

Volume II

List of Contributors, ix

Preface, xvii

Acknowledgments, xix

About the Editor, xxi

27 Pathogenesis of Haemophilus influenzae in Humans, 517
Alistair Harrison and Kevin M. Mason

28 Campylobacter jejuni: Molecular Mechanisms and Animal Models of Colonization and Disease, 535
Christopher R. Gourley and Michael E. Konkel

29 Pathogenesis of Francisella tularensis in Humans, 555
Monique Barel, Nathalie Grall, and Alain Charbit

30 Pathogenesis of Yersinia pestis in Humans, 567
E.D. Williamson

31 Pathogenesis of Legionella pneumophila in Humans, 575
Adam J. Vogrin and Elizabeth L. Hartland

32 Pathogenesis of Kingella kingae Infections, 591
Pablo Yagupsky

33 Pathogenesis of Helicobacter pylori in Humans, 607
Carlo–Federico Zambon, Daniela Basso, Michela Pelloso, Alberto Tessari, and Mario Plebani

34 Pathogenesis of Chlamydia trachomatis in Humans, 635
Luis Otero Guerra, Jose Antonio Boga, Jonathan Fernandez Suarez, Carlos Fernandez Benitez, and Fernando Vazquez

35 Pertussis or Whooping Cough, 649
Camille Locht and Nathalie Mielcarek

36 Pathogenesis of Human Ehrlichioses, 665
Tais Berelli Saito and David H. Walker

37 Neisseria gonorrhoeae: The Pathogen, Diagnosis, and Antimicrobial Resistance, 683
Namraj Goire, David J. Speers, Monica M. Lahra, and David M. Whiley

38 Pathogenesis of Corynebacterium diphtheriae and Corynebacterium ulcerans, 699
Andreas Burkovski

39 Pathogenesis of Staphylococcus aureus in Humans, 711
Thea Lu and Frank R. DeLeo

40 Pathogenesis of Listeria monocytogenes in Humans, 749
Helene Marquis, Douglas A. Drevets, Michael S. Bronze, Sophia Kathariou, Thaddeus G. Golos, and J. Igor Iruretagoyena

41 Anthrax Infection, 773
Kenneth E. Remy, Caitlin Hicks, and Peter Q. Eichacker

42 Pathogenesis of Streptococcus in Humans, 795
Roberta Creti, Giovanni Gherardi, Alberto Berardi, and Lucilla Baldassarri

43 Pathogenesis of Clostridium botulinum in Humans, 821
Sabine Pellett

44 Mycobacterium ulcerans and Buruli Ulcer, 841
Mark Eric Benbow, Belinda Hall, Lydia Mosi, Sophie Roberts, Rachel Simmonds, and Heather Williamson Jordan

45 Challenges Associated with Diagnostics, Drug Resistance, and Pathogenesis of Mycobacterium tuberculosis, 863
Juan Carlos Palomino and Anandi Martin

46 Pathogenesis of Orientia tsutsugamushi Infection in Humans, 877
Wiwit Tantibhedhyabgkul and Jean–Louis Mege

47 Lyme Borreliosis, 887
John J. Halperin

48 NDM–Type Carbapenemases in Gram–Negative Rods, 897
Laurent Dortet, Laurent Poirel, and Patrice Nordmann

49 Pathogenesis of Cryptococcosis in Humans, 915
Ricardo Negroni and Alicia I. Arechavala

50 Candida albicans: Clinical Relevance, Pathogenesis, and Host Immunity, 929
Alexandra Correia, Paula Sampaio, Manuel Vilanova, and Celia Pais

51 Pathogenesis of Pneumocystis jirovecii Pneumonia, 953
Taylor Eddens, Aniket Kaloti, and Jay K. Kolls

52 Pathogenesis of Aspergillosis in Humans, 967
George Dimopoulos, Dimitrios K. Matthaiou, Nikolaos Moussas, Olympia Apostolopoulou, George Arabatzis, Aristea Velegraki, and Garyphalia Poulakou

Index, i1

O autorze

THE EDITOR

Sunit K. Singh, Ph.D is an Associate Professor (Molecular Immunology) in the Molecular Biology Unit, Faculty of Medicine, Institute of Medical Sciences , Banaras Hindu University (BHU), Varanasi, India.

Blurb

Emerging and re–emerging pathogens pose several challenges to diagnosis, treatment, and public health surveillance, primarily because pathogen identification is a difficult and time–consuming process due to the novel nature of the agent. Proper identification requires a wide array of techniques, but the significance of these diagnostics is anticipated to increase with advances in newer molecular and nanobiotechnological interventions and health information technology.

Human Emerging and Re–emerging Infections covers the epidemiology, pathogenesis, diagnostics, clinical features, and public health risks posed by new viral and microbial infections. The book includes detailed coverage on the molecular mechanisms of pathogenesis, development of various diagnostic tools, diagnostic assays and their limitations, key research priorities, and new technologies in infection diagnostics. Volume 1 addresses viral and parasitic infections, while volume 2 delves into bacterial and mycotic infections.

Human Emerging and Re–emerging Infections is an invaluable resource for researchers in parasitologists, microbiology, Immunology, neurology and virology, as well as clinicians and students interested in understanding the current knowledge and future directions of infectious diseases.

Covers emerging and re–emerging viral, parasitic, fungal, and bacterial infections

Includes detailed descriptions of diagnostic tools used in pathogen detection

Points the way forward for new diagnostic tools for emerging and re–emerging infections

Encompasses a variety of diagnostic techniques including cell cultures, animal inoculation, cultivation in artificial media, histopathological evaluation of tissues, serological techniques using surrogate antigens and advanced molecular biology based approaches

An invaluable resource for clinicians, instructors, basic and applied scientists, students, and established researchers