Notes on Contributors viiPreface to the First Edition ixPreface to the Ninth Edition xAbout the Companion Website xiPart 1 Introducing Pharmaceutical Microbiology 11 Introduction to Pharmaceutical Microbiology 3Brendan F. Gilmore and Stephen P. DenyerPart 2 Biology of Microorganisms 112 Fundamental Features of Microbiology 13Norman Hodges and Stephen P. Denyer3 Bacteria 27David Allison4 Fungi 47Kevin Kavanagh5 Viruses and Other Acellular Infectious Agents: Characteristics and Control 63Timofey Skvortsov and Jean-Yves Maillard6 Protozoa 98Tim PagetPart 3 Pathogens and Host Response 1217 Principles of Microbial Pathogenicity and Epidemiology 123David Allison and Andrew J. McBain8 Microbial Biofilms: Consequences for Health 135Brendan F. Gilmore9 Immunology 147Mark Gumbleton and Mathew W. Smith10 Vaccination and Immunisation 174Gavin J. Humphreys and Andrew J. McBainPart 4 Prescribing Therapeutics and Infection Control 19111 Antibiotics and Synthetic Antimicrobial Agents: Their Properties and Uses 193Brendan F. Gilmore12 Mechanisms of Action of Antibiotics and Synthetic Anti-infective Agents 232Peter Lambert13 Bacterial Resistance to Antibiotics 249Brendan F. Gilmore and Stephen P. Denyer14 Clinical Uses of Antimicrobial Drugs 272Hayley Wickens and Conor Jamieson15 Antibiotic Prescribing and Antimicrobial Stewardship 289Rebecca Craig16 Infection Prevention and Control: Healthcare-associated Infection 304Elaine Cloutman-GreenPart 5 Contamination and Contamination Control 32117 Microbial Spoilage, Infection Risk and Contamination Control 323Rosamund M. Baird18 Chemical Disinfectants,Antiseptics and Preservatives 343Sean P. Gorman and Brendan F. Gilmore19 Laboratory Evaluation of Antimicrobial Agents 365Brendan F. Gilmore and Sean P. Gorman20 Microbicides: Mode of Action and Resistance 385Stephen P. Denyer and Jean-Yves Maillard21 Sterilisation Procedures and Sterility Assurance 403Alistair K. Brown and Stephen P. DenyerPart 6 Pharmaceutical Production 43322 Sterile Pharmaceutical Products and Principles of Good Manufacturing Practice 435Tim Sandle23 The Manufacture and Quality Control of Immunological Products 462Tim Sandle24 Recombinant DNA Technology 480Miguel Cámara and Stephan HeebPart 7 Current Trends and New Directions 50725 The Wider Contribution of Microbiology to the Pharmaceutical Sciences 509Mathew W. Smith, James C. Birchall and Sion A. Coulman26 Alternative Strategies to Antibiotics: Priorities for Development 529Brendan F. GilmoreIndex 544
Brendan F. Gilmore, Ph.D is Professor of Pharmaceutical Microbiology at Queen's University of Belfast, UK.Stephen P. Denyer, Ph.D is Emeritus Professor of Pharmacy at the Universities of Brighton and Sussex, Brighton, UK.