Hormones and Signaling: Volume 1

ISBN-13: 9780123124111 / Angielski / Twarda / 1997 / 364 str.

Bert W. O'Malley; Tony Hunter; James Darnell

Opis

Hormones and Signaling focuses on the mechanism of gene regulation at the cellular level. It also covers the way hormones act to modulate gene regulation and animal development.

Includes information on:

• Nuclear receptors, coactivators, and corepressors
• Membrane receptors, kinases, and phosphorylation on cascades
• Hormonal regulation of development
• Calcium channels and neurotransmitters
• Chromatin, transcription factors, and regulation of gene expression
• JAK/STAT pathways
• Hormone-regulated development and gene "knock-out"

Recenzje

"The editors and contributors are all well-known leaders in their disciplines. I enjoyed reading this book and I am sure that I will use it often as a reference tool. Chapters are generally well-written, interesting, and comprehensive... I look forward to future volumes in the series... I recommend this book as a valuable reference tool for all interested in endocrine signaling pathways." --TRENDS IN ENDOCRINOLOGY AND METABOLISM

"...it fills a particular niche by providing a rapid update on specialized aspects of the challenging field of regulatory biology." --CELL

Spis treści

E.B. Thompson, Glucocorticoid and Oxysterol-induces Apoptosis of Lymphoid Cells.
A.M. Schmidt, J-L. Wautier, D.M. Stern, and S.D. Yun, RAGE: A Receptor with a Taste for Multiple Ligands and Varied Pathophysiologic States.
R.J. Lefkowitz and A.D. Macrae, The Function and Regulation of the G Protein-Coupled Receptor Kinases.
G. Kuiper, S. Nilsson, and J-A. Gustafsson, Characteristics and Function of the Novel Estrogen Receptor beta.
M.E. Lippman and C.Tang, EGF Family Receptors and Their Ligands in Human Cancer.
D.L. Garbers and T.A. Quill, Fertilization: Common Molecular Signaling Pathways Across the Species.
A. Minden and M. Karin, The JNK Family of MAP Kinases: Regulation and Function.
P. Devchand and W. Wahli, PPAR alpha: Tempting Fate with Fat.
S.R. Datta and M.E. Greenberg, Molecular Mechanisms of Neuronal Survival and Apoptosis.
D.J. Mangelsdorf and P.J. Willy, Nuclear Orphan Receptors: The Search for Novel Ligands and Signaling Pathways.