Hormone Replacement Therapy and Cancer: The Current Status of Research and Practice

ISBN-13: 9781842140796 / Angielski / Twarda / 2002 / 294 str.

Andrea R. Genazzani; A. R. Genazzani

Opis

Leading specialists have contributed their knowledge in this book, regarding the effects of hormones on women and possible cancer risks. Topics include carcinogenesis, HRT and breast cancer, endometrical cancer, colon cancer, melanoma, and epithelial ovarian cancer. It concludes with a discussion of the benefits and risks of specific therapies.

Recenzje

'A collection of short, succinctly written chapters, mostly by European scientists and clinicians, that cover a wide variety of topics, including colon cancer. With a field as difficult to grasp and rapidly changing as hormone replacement therapy and cancer, these useful chapters serve to put the reader in the ballpark and identify the players.' - New England Journal of Medicine

Spis treści

CARCINOGENESIS Oncogenes and Tumor Suppressor Genes, S. Giordano, S. Corso, and P. Conrotto Telomerase and Cancer, S.S.R. Banik and C. Counter GrowthFactors, R. Radinsky Matrix Metalloproteinases, S. McDonnell, A. O' Connor, D. Murray, and C.C. Lynch Biological Basis of Angiogenesis and Role of Vascular Endothelial Growth Factor-D, S. Oliviero HRT AND BREAST CANCER Breast Cancer: Epidemiology, Pathology and Natural History, R.K. Ross Genes and Heredity in Breast Cancer, G. Bevilacqua Endocine, Paracrine and Intracine Mechanisms of Growth Regulation in Normal and Malignant Breast Epithelium, J. Pasqualini and G.S. Chetrite Chemoprevention of Breast Cancer with Tamoxifen: Recent Experience and Future Perspectives, B. Bonanni, A. Guerrieri-Gonzaga, N. Rotmensz, and A. Decensi Breast Cancer: Endocrine Therapy, A. Hamilton Hormone Replacement Therapy and Mammographic Breast Density, B. von Schoulz and E. Lundstr÷m HRT, IGF-1 and Breast Cancer, P. Sismondi, N. Biglia, and P. Ponzone, and S. Ambroggio Hormone Replacement Therapy and Risk of Breast Cancer, P. Kenemans The Use of Hormone Replacement Therapy for Management of Severe Postmenopausal Symptoms Following Breast Cancer, B. Wren HRT AND ENDOMETRIAL CANCER Endometrial Cancer: Epidmiology, Pathology and Natural History, J. Prat Endocrine, Paracrine and Intracrine Mechanisms of Growth Regulation in Normal and Malignant Endometrial Epithelium, E.-M. Rutanen Chemoprevention and Endocrine Therapy of Endometrial Carcinoma, A.R. Genazzani and A. Gadducci Hormone Replacement Therapy and Endometrial Cancer, C. Burger Endometrial Stromal Tumors - Are They Hormonally Sensitive? P.E. Schwartz, M.C. Chu, W. Zheng and G. Mor HRT AND COLON CANCER Colon Cancer: Epidemiology, M.E. Leon Colon Cancer: Pathology and Natural History, F. Tonelli Estrogen Receptors, Estrogens and Colon Cancer, F. Al-Azzawi Cyclo-Oxygenase-2: An Endogenous Tumor Promotor and Target for the Chemoprevention of Colorecta l Cancer and Other Neoplastic Diseases, F. Marks Hormone Replacement Therapy and Colon Cancer, A. Wu HRT AND MELANOMA Cutaneous Malignant Melanoma: Epidemiology, Endocrine Features and Hormone Replacement Therapy, A. Gadducci and A.R. Genazzani HRT AND EPITHELIAL OVARIAN CANCER Ovarian Cancer: Epidemiology, Pathology and Natural History, S. Pecorelli BRCA1 AND BRCA2 and Ovarian Cancer, S. Greggi Endocrine, Paracrine and Intracine Mechanisms of Growth Regulation in Normal and Malignant Ovarian Epithelium, R.C. Bast Estrogen Replacement Therapy Use and Risk of Ovarian Cancer: Results From Two Italian Studies and Review of Literature, F. Parazzini, G. Polverine, S. Cipriani, E. Ricci, F.Chiaffarino and C. la Vecchia SELECTIVE ASPECTS OF SPECIFIC THERAPIES Understanding HRT Risks and Benefits and the New Science of HRT: A Breast Cancer Analysis, J. Fiorica Pulsed Estrogen Therapy May Lead to a Lower Breast Stimulation Than Daily Continuous Esposure, N. Mahon Mammographi c Density Under Different HRT Regimens: Data From the Randomised Clinical Trial, H. Junkermann Transdermal HRT and the Risk of Breast Cancer and Endometrial Cancer, M. Notelovitz The Effects of Selective Estrogen Receptor Modulators on the Endometrium, S.R. Goldstein The Safety and Tolerability Profile of Livial, E.A. Helmond and J.H. Kloosterboer Effects of Progesterone Receptor Antagonists on Breast Cancer, J. Hoffmann More Than Bones: HRT for Mind and Body, J.M. Alt Index

O autorze

Andrea R. Genazzani (Author)