Herpes Simplex Virus Epithelial Keratitis: In Vivo Morphology in the Human Cornea

ISBN-13: 9783642010118 / Angielski / Miękka / 2009 / 58 str.

Helena M. Tabery

Opis

As a young ophthalmologist, I found corneal epithelial diseases a subject diffcult to grasp. One day, it occurred to me that the reason might be a lack of images showing the nature of the components of the changes visible with the slit lamp. With the slit lamp, the inevitable eye movements that blur the image limited the magnifcation level, but perhaps photography might be the answer. It was not a short journey, but in the end the idea proved right. By trial and error, the quality of the images improved, and after some time, I found that the resolution allowed reasonable comparisons with available images of histological preparations. Such comparisons allowed better und- standing of the substructures of epithelial in vivo lesions and, in conjunction with their in vivo dynamic features, eventually an understanding of at least some mechanisms behind them. This book, originating from over 20 years of experience with observations of ocular surface changes at high magnifcation level, covers several aspects of corneal epithelial lesions caused in humans by herpes simplex virus: various shapes of the lesions, their substructure and mechanisms behind them; morphological features of the healing p- cess, sequelae, complications, and some accompanying signs; and some rare cases. For those less familiar with the slit lamp image, I have added explanatory drawings to facilitate comprehension.

Recenzje

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Spis treści

The Morphology of Herpes Simplex Virus Epithelial Keratitis.- Healing of Herpes Simplex Virus Epithelial Keratitis Treated with Acyclovir Ointment and Short-Term Sequelae of the Infection.- Complications, Accompanying Signs, Recurrences, and Long-Term Sequelae of Herpes Simplex Virus Epithelial Keratitis.

Blurb

Herpes Simplex Virus Epithelial Keratitis provides a kind of ‘living histology’, revealing both morphological and dynamic features of the disease, and explaining the mechanisms behind them. 

It discusses in detail:
° the result of herpes simplex virus impact on the living human epithelium
° the step-by-step dynamics of healing during a successful treatment
° the complications and sequelae of infection

The case studies presented demonstrate the application of these observations in clinical practice. This unique guide offers insights helpful in differential diagnostics and the recognition of lesser known variants, as well as complications. It is also useful for the follow–up of treatment results and the differentiation between an active infection and sequelae. It is an invaluable aid for ophthalmologists and researchers working with ocular surfaces.