Herbal dipeptidyl peptidase-4 inhibitors for Alzheimer's disease

ISBN-13: 9783659762505 / Angielski / Miękka / 2015 / 124 str.

Kosaraju Jayasankar;Basavan Duraiswamy

Opis

A growing body of evidence shows that pharmacological agents used for the treatment of type-2-diabetes such as dipeptidyl peptidase-4 inhibitors have become valuable candidates as disease modifying agents in the treatment of Alzheimers disease. This book deals with a study investigates the neuroprotective roles of Pterocarpus marsupium and Eugenia jambolana as dipeptidyl peptidase-4 inhibitors in streptozotocin induced Alzheimers disease. Our finding suggests that Pterocarpus marsupium and Eugenia jambolana are the potential cognitive enhancers against streptozotocin induced Alzheimers disease by dipeptidyl peptidase-4 inhibitory action and their neuroprotective action attributed through increase in active glucagon-like peptide-1 levels.

O autorze

Dr. Kosaraju obtained his PhD degree in 2014 from JSS College of Pharmacy, Ooty, India (JSS University). He has developed expertise in the areas of behavioral assessment tests, intracerebroventricular injection in preclinical species. Dr. Kosaraju has an excellent academic record, research experience and is well versed with modern technologies.