"This monograph covers the management of the critically ill patient with liver disease based on a summary of physiological alternations in this condition. ... Because of its readability, this book is appropriate for postgraduate providers with all degrees of sophistication. ... This is an excellent overview of both the pathology of liver disease and the implications for other organ systems supported by the intensivist. Presentations are well written and summarize clinical problems and their management effectively." (David J. Dries, Doody's Book Reviews, April, 2018) "This book provides an overview of both the pathophysiological background of liver disease and its effects on other systems. It offers background knowledge and clinical management. It has an admirable didactic approach that is comprehensive enough to provide all essential information, while succinct enough to still be considered concise." (Ashraf A. Dahaba and Helmar Bornemann-Cimenti, Anesthesia & Analgesia, Vol. 128 (1), January, 2019)
Normal Hepatic Function and Physiology.- Circulatory Physiology in Liver Disease.- Respiratory Physiology in Liver Disease.- Gastrointestinal and Hepatic Physiology in Liver Disease.- Renal Physiology in Acute and Chronic Liver Disease.- Cerebrovascular Physiology in Liver Disease.- Definition, Epidemiology, Natural History and Prognostication of Liver Disease.- Brain and the Liver- Cerebral Edema, Hepatic Encephalopathy and Beyond.- Cardiovascular Alterations in Acute and Chronic Liver Failure.- Gastrointestinal Complications in Liver Disease.- Respiratory Complications in Acute and Chronic Liver Disease.- Renal Complications in Acute and Chronic Liver Disease.- Hematological Complications in Liver Disease.- Nutrition in Liver Disease.- Infectious Complications in Liver Disease.- Pharmacological Considerations in Liver Failure.- Non Transplant Surgical Considerations: Hepatic Surgery and Liver Trauma.- Anesthetic and Perioperative Considerations in the patient with liver disease (Non Transplant).- Perioperative Considerations during Liver Transplantation.- Use of Extra-Corporeal Liver Support Therapies.- Assessing Liver Function in the Critically Ill Patient.
Dr. Nanchal is Associate Professor of Medicine and serves as the director of the medical intensive care unit and critical care fellowship program at Froedtert and The Medical College of Wisconsin. He has a special interest in the care of patients with hepatic critical illness and his research focuses on outcomes of critically ill patients.
Dr. Ram Subramanian is Associate Professor of Medicine and Surgery at the Emory University School of Medicine in Atlanta USA. He is the Medical Director of Liver Transplantation and oversees the Liver Critical Care services at the Emory Liver Transplant Center. His fellowship training involved combined training in Pulmonary & Critical Care Medicine and Gastroenterology & Transplant Hepatology, with a goal to focus his clinical and research interests in the field of hepatic critical care. Over the course of his academic career, he has developed a specific clinical and research expertise in extracorporeal liver support.
This book focuses on the critical care of the patient with acute, acute on chronic and chronic liver failure as well as the peri-operative care of the patient with liver transplantation. Each of these disease processes is unique in pathophysiological manifestations, underpinnings of physiology and treatment options.
Patients with acute, chronic or acute on chronic liver failure are a growing fraction of ICU admissions. Hepatic Critical Care serves as the essential reference for both practicing intensivists at community hospitals and tertiary referral centers. This textbook is also targeted towards trainees specifically interested in taking care of patients with liver disease and liver transplantation.
