Hemopoietic Dysplasias (Preleukemic States)

ISBN-13: 9783540075974 / Angielski / Miękka / 1977 / 360 str.

M. Bessis; G. Brecher

Spis treści

Preleukemic States.- Preleukemic States.- Section I: Clinical and Hematological Data.- The Preleukemic Syndrome: Clinical and Laboratory Features, Natural Course, and Management.- Preleukemic States. I. Definition and Classification. II. Refractory Anemia with an Excess of Myeloblasts in the Bone Marrow (Smoldering Acute Leukemia).- Discussion of papers by Linman, Bagby, and Dreyfus.- Preleukemic States in Atomic Bomb Survivors in Japan.- Discussion.- Acute Myeloblastic Leukemia after Immunodepressive Therapy for Primary Nonmalignant Disease.- Discussion.- Preleukemia: Does it Exist?.- Discussion.- Section II: New Techniques and Special Investigations.- Prediction of Relapse and Remission in AML by Marrow Culture Criteria.- Discussion.- In vitro Colony Growth of Acute Myelogenous Leukemia.- The Use of the Robinson in vitro Agar Culture Assay in Adult Acute Leukemia.- Significance of PHA Induced Clonogenic Cells in Chronic Myeloid Leukemia and Early Acute Myeloid Leukemia.- Discussion of papers by Dicke et al. and Spitzeret al.- An Approach to Human Preleukemia Using Cell Culture Studies.- Discussion.- Comparative Electron-Microscopic Study of the Erythrocytic Line in Refractory Anemia (Preleukemia) and Myelomonocytic Leukemia.- Cytochemical and Ultrastructural Studies of Aberrant Granules in the Neutrophils of Two Patients with Myeloperoxidase Deficiency during a Preleukemic State. Relationship to Abnormal Bactericidal Activity.- Discussion of papers by Maldonado et al and Breton-Gorius et al.- Blood Groups Changes in Preleukemic States.- The Cellular Distribution of Erythrocyte and Normoblast A1and A Antigens in Normal and Preleukemic States. An Immunoelectron Microscopy Study.- Abnormal Distribution of Erythrocytes A1 Antigens in Preleukemia as Demonstrated by an Immunofluorescence Technique.- Discussion of papers by Salmon, Gourdin et al. and Rochant et al.- Cell Membrane Antigens Associated with Human Adult Acute Leukemia.- Discussion.- Section III: Pathophysiology.- Notions about Human Stem Cells.- Discussion.- Preleukemic States in the Light of the Leukemia Cytokinetics.- Discussion.- The Role of Lymphoid and Haematopoietic Target Cells in Viral Lymphomagenesis of C57BL/Ka Mice. I. Susceptibility to Viral Replication.- The Role of Lymphoid and Haematopoietic Target Cells in Viral Lymphomagenesis of C57BL/Ka Mice. II. Neoplastic Transformation of Bone Marrow-Derived Cells in the Thymic Microenvironment.- Discussion of papers by Lieberman and Kaplan.- Oncogenesis in Human Acute Leukemia.- Discussion.- Problems Relating to Immunoselection of Leukemias.- Discussion.- Section IV: General Discussion.- I. Is Preleukemic States an Adequate Designation?.- II. Should Hemopoietic Dysplasias be Treated?.- III. A Registry for Hemopoietic Dysplasias.