Hematopoietic Stem Cell Niche: Volume 1

ISBN-13: 9780128113752 / Angielski / Miękka / 2017 / 186 str.

Dominique Bonnet

Opis

Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols. This series addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments, such as new data on disease and clinical applications. Specific chapters delve into the evolution of hematopoietic stem cell niches, the role of CNS in the regulation of HSCs, and targeting the bone marrow niche in hematological malignancies. In addition, video content illustrates protocols, transplantation techniques, and work with mice.

• Explores not only reviews of research, but also shares methods, protocols, and transplantation techniques
• Contains video content to illustrate such areas as protocols, transplantation techniques, and work with mice
• Each volume concentrates on one organ, making this a unique publication

Spis treści

1. Stroma Cell Niche Regulation During HSC Development G. Stik, P. Charbord and C. Durand 2. The Evolvement of Hematopoietic Stem Cell Niches B.O. Zhou, L. Li and M. Zhao 3. The Role of the CNS in the Regulation of HSCs A. García-García and S. Méndez-Ferrer 4. Imaging the Haematopoietic Stem Cell Niche D. Duarte and C.L. Celso 5. Mechanisms of Hematopoietic Stem and Progenitor Cells Bone Marrow Homing and Mobilization A. Kumari, T. Lapidot, K. Golan, E. Khatib-Massalha and O. Kollet 6. Alterations of HSC Niche in Myeloid Malignancies L. Han and M. Konopleva 7. Targeting the Bone Marrow Niche in Hematological Malignancies D. Verma and D.S. Krause

O autorze

Dominique Bonnet is a Senior Group Leader at the Francis Crick Institute. She is also Professor at the University College of London and a Senior Lecturer at the Institute of Child Health.