Hematopathology: Genomic Mechanisms of Neoplastic Diseases

ISBN-13: 9781617797088 / Angielski / Miękka / 2012 / 360 str.

Domnita Crisan

Opis

Hematopathology: Genomic Mechanisms of Neoplastic Diseases will keep physicians abreast of the rapid and complex changes in genomic medicine, as exemplified by the molecular pathology of hematologic malignancies. This timely volume will update physicians on the complexities of genomic lesions, as well as offer an integrated framework encompassing molecular diagnosis, the new WHO classification of hematologic neoplasms with focus on molecular pathology, prognostic value of molecular tests, and molecular monitoring of response to gene-targeted therapy. As such, it will be of great value to hematologists, oncologists, pathologists, internal medicine and pediatric specialists, as well as bioscientific staff and laboratorians in private hospitals and academic institutions.

Recenzje

From the reviews:

"This book addresses the current knowledge of genomics as applied to the pathogenesis, diagnosis, prognosis, monitoring, and targeted therapy of hematologic malignancies. ... the book is intended for molecular pathologists, hematopathologists, general surgical pathologists, pathology residents, and hematopathology fellows. ... This is a good, quick reference for practicing pathologists dealing with hematologic specimens. ... the book is quite easy to read, as it is written primarily for practicing pathologists. ... book is certainly suitable for departmental libraries and the shelves of practicing pathologists." (Anamarija M. Perry, Doody's Review Service, April, 2011)

"It gives basic information about the techniques available and a detailed overview of molecular changes in particular hematological malignant diseases. ... Anybody working in this field, irrespective if in research, laboratory diagnostics or clinical treatment, will welcome this book, because the relevant information can be found here quickly and easily. ... recommended for residents, fellows in training as well as for specialist looking for information from the field of interest they do not deal with daily. It should not be missing in any hematological department." (M. Hrubisko, Neoplasma, March, 2011)

Spis treści

Chapter 1: Molecular techniques used in Hematopathology

Chapter 2: Cytogenetics techniques used in Hematopathology

Chapter 3: The molecular component of the new WHO classification of hematologic malignancies

Chapter 4: Molecular pathology of pediatric acute leukemias

Chapter 5: Molecular pathology of adult acute leukemias

Chapter 6: Molecular pathology of lymphomas

Chapter 7: Molecular pathology of chronic myeloproliferative neoplasms

Chapter 8: Molecular pathology of CLL

Chapter 9: Targeted therapy in hematologic malignancies

Chapter 10: MicroRNAs in hematologic malignancies