Helicobacter Pylori in Human Diseases: Advances in Microbiology, Infectious Diseases and Public Health Volume 11

ISBN-13: 9783030219185 / Angielski / Miękka / 2020 / 284 str.

Shigeru Kamiya; Steffen Backert

Spis treści

1. Genomic diversity of Helicobacter pylori and human migrations

Yoshio Yamaoka(Oita University, Japan) E-mail: yyamaoka@oita-u.ac.jp

2. Epidemiology, diagnosis and risk factors of Helicobacter pylori infections

Eliette Touati (Pasteur Institute, France) E-mail: eliette.touati@pasteur.fr

3. Activities and functional importance of Helicobacter pylori virulence factors

Dionyssios Sgouras (Pasteur Institute, France) E-mail: dionsgouras@gmail.com

4. Structural and functional aspects of the Helicobacter pylori proteome

Giuseppe Zanotti (University of Padova, Italy) E-mail: giuseppe.zanotti@unipd.it

5. Role of adhesion to epithelial cells in gastric colonization by H. pylori

Eric Sundberg (University of Maryland, USA) E-mail: esundberg@ihv.umaryland.edu

6. Interplay of Helicobacter pylori with immune cells: impact on gastric pathology

Steffen Backert  (Friedrich-Alexander University Erlangen, Germany) E-mail: Ebook-Helicobacter@gmx.de

7. Helicobacter pylori infection of children

Masumi Okuda (Aichi Medical University, Japan) E-mail: okuda@naxnet.or.jp

8. Non-malignant Helicobacter pylori-associated diseases

Michael Vieth (Institute of Pathology, Germany) E-mail: vieth.lkpathol@uni-bayreuth.de

9. Malignant Helicobacter pylori-associated diseases: gastric cancer and MALT lymphoma

Masanori Hatakeyama (The University of Tokyo, Japan) E-mail: mhata@m.u-tokyo.ac.jp

10. Host genetic polymorphisms in gastric disease outcome

Margeruite Clyne (University College Dublin, Ireland) E-mail: marguerite.clyne@ucd.ie

11. Helicobacter pylori genetic polymorphisms in gastric disease development

Scott Merrell (Uniformed Services University of the Health Sciences, USA) E-mail: douglas.merrell@usuhs.edu

12. Crosstalk of Helicobacter pylori with the gastrointestinal microbiota

Ceu Figueiredo (University of Porto, Portugal) E-mail: cfigueiredo@ipatimup.pt

13. Treatment of Helicobacter pylori infection

Akiko Shiotani  (Kawasaki Medical University, Japan) E-mail: shiotani@med.kawasaki-m.ac.jp

14. Role of probiotics in eradication therapy for Helicobacter pylori infection

Shigeru Kamiya (Kyorin University, Japan) E-mail: skamiya@ks.kyorin-u.ac.jp

15. Immunity and vaccine development against Helicobacter pylori

Anna Walduck (RMIT University, Australia) E-mail: anna.walduck@rmit.edu.au

O autorze

Shigeru Kamiya (Kyorin University, Japan)

Steffen Backert (Friedrich-Alexander University Erlangen, Germany)

Blurb

This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. 

H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood.

Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.