Helicobacter Pylori and Gastroduodenal Pathology

ISBN-13: 9783642774881 / Angielski / Miękka / 2012 / 400 str.

Jose M. Pajares; A. Salvador Pena; Peter Malfertheiner

Opis

In the rapidly evolving field of Helicobacter infection new data on pathogenetic and pathophysiological mechanism have appeared. New methods which will be more sensitive and specific in the diagnosis of the infection are being developed and in this proceedings the first attempt using PCR technology is published. From the clinical point of view, a challenging aspect that needs clarification, is the observation which suggests an appearance of a correlation between the presence of the bacteria and abdominal pain and other symptoms in children whereas in old age no such correlation is evident. The relationship of H. pylori and gastric cancer is studied with histopathological data and epidemiological approaches. On the treatment side schemes using short courses and new antibiotic combinations are being investigated and preliminary data are reported.

Spis treści

I. Microbiology.- Helicobacter pylori Detection by Polymerase Chain Reaction of the Gene Encoding 16S Ribosomal RNA in Fresh and Paraffin-Embedded Material.- Polymerase Chain Reaction for Helicobacter pylori.- Helicobacter pylori Strains from Duodenal Ulcer Patients Differ at the Genomic Level from Those Patients with Simple Gastritis.- Perspectives on the Microbiology of Helicobacter pylori.- II Epidemiology.- A Descriptive Study of the Characteristics of People with Helicobacter pylori Infection.- High Prevalence of Helicobacter pylori-Induced Gastritis in China: Results of a Screening Study in 194 Adolescents.- Seroepidemiology of Helicobacter pylori Infection in Vegans and Meat Eaters.- Seroepidemiology of Helicobacter pylori Infection in the Armed Forces.- Helicobacter pylori Infection Clusters in Families of Healthy Individuals.- Reinfection with Helicobacter pylori Due to Intrafamilial Clustering of the Organism.- Epidemiology: Summary of Workshop and Future Prospects.- III. Pathophysiology.- Superficial Components from Helicobacter pylori That Are Adherent to Epithelial Cells.- Bismuth Bioavailability from 205Bi-Labelled Bismuth Compounds Used in Suppression of Helicobacter pylori and Treatment of Peptic Ulcer.- Optical and Electronic Findings in Helicobacter pylori Infection of Antral Mucosa.- Bacteria and Gastrin Release.- Helicobacter pylori, Gastritis, Duodenal Ulcer, and Gastric Histamine Content.- Detection of Phospholipases and Cytotoxic Activities of Helicobacter pylori.- IV. Pathology.- Antral Follicular Gastritis Is Characteristic of Helicobacter pylori Infection.- Defining the Role of Helicobacter pylori in Relationship to Relapse of Duodenal Ulcer.- Gastritis and Helicobacter pylori Prevalence in Patients with Heterotopic Gastric Mucosa or Gastric Metaplasia in the Duodenum.- Evolution of Gastritis After Helicobacter pylori Eradication.- Histological Improvements in Gastritis After Eradication of Helicobacter pylori Infection.- Helicobacter pylori in Subtotal Gastrectomies.- Helicobacter pylori and Duodenal Ulcer.- Helicobacter pylori and the Oesophagus.- Gastritis: A Short Appraisal of Classification and the Sydney System.- V. Immunology.- Stress Proteins and Local Immune Response in Helicobacter pylori-Associated Chronic Gastritis.- Local and Systemic Antibody Responses During Helicobacter pylori Infections.- Local Immunoglobulin A Subclass Alteration in the Gastric Mucosa of Helicobacter pylori-Infected Patients.- Antibodies Against Helicobacter pylori as an Indicator of Antrum Gastritis.- Antibodies to Vacuolating Toxin of Helicobacter pylori in Dyspeptic Patients.- Cytokines and Mucosal Immune Responses to Helicobacter pylori.- Immunological Aspects of Helicobacter pylori Infection.- VI. Diagnostic Progress.- Usefulness of Two Enzyme-Linked Immunosorbent Assay Systems for the Diagnosis of Helicobacter pylori-Associated Gastritis.- VII Helicobacter pylori and Non-ulcer Dyspepsia.- Helicobacter pylori Infection in Gastroesophageal Reflux Disease.- Computerised History Taking for the Assessment of Helicobacter pylori in Non-ulcer Dyspepsia: The Quest for the Clinical Syndrome.- VIII. Helicobacter pylori and Malignant Growth.- Prevalence of Helicobacter pylori in Patients with Malignant Growth of Gastric Mucosa.- A Role for Helicobacter pylori in Gastric Carcinoma?.- Increased Incidence of Helicobacter pylori in Gastric Cancer, as Shown by the Rapid Urease Test.- Evaluation of the Presence and Amount of Helicobacter pylori in Early Gastric Cancer.- Helicobacter pylori prevalence in Patients with Severe Dysplasia of Gastric Epithelium and Associated Pathology.- Gastric Cancer and Helicobacter pylori.- Role of Helicobacter pylori in Gastric Carcinogenesis: Future Prospects.- IX. Helicobacter pylori in Children.- Epidemiology of Helicobacter pylori Infection in Pediatrics: A Serologic Study.- Prevalence of Antibody of Helicobacter pylori in Children in Northern Nigeria.- Prevalence of Immunoglobulin G Antibodies to Helicobacter pylori in Mothers of Newborns with Upper Gastrointestinal Bleeding.- Helicobacter pylori Infection in Children.- Histological and Serological Examination of Helicobacter pylori in Estonian Children with Abdominal Complaints.- Helicobacter pylori in Children with Recurrent Abdominal Pain and Other Conditions.- Helicobacter pylori-Associated Gastritis in Children.- Helicobacter pylori Gastritis in Children: Wide Spectrum of Symptoms.- Childhood Peptic Ulcer Can Be Cured by Eradicating Helicobacter pylori.- Helicobacter pylori Infection and Gastroduodenal Pathology in Children.- X. Treatment.- Solubility Characteristics of Different Bismuth Salts in Gastric Juice.- Assessment of Susceptibility of Helicobacter pylori to Tinidazole, Amoxicillin and Tetracycline Among 555 Patients.- In Vivo Acquired Resistance to Fluorquinolones in Helicobacter pylori During Therapy with Ciprofloxacin Alone or Ciprofloxacin plus Amoxicillin Clavulanate.- Treatment of Helicobacter pylori-Positive Lesions: 13C-Urea Breath Test Monitoring and Morphology.- Colloidal Bismuth Subcitrate Plus Amoxicillin Versus Colloidal Bismuth Subcitrate plus Ofloxacin in the Treatment of Chronic Antral Gastritis Positive for Helicobacter pylori.- Factors Affecting Eradication of Helicobacter pylori with Triple Therapy.- Comparison of Three Triple Therapies in the Eradication of Helicobacter pylori.- Ciprofloxacin-Omeprazole Treatment for Eradication of Helicobacter pylori.- Amoxicillin-Omeprazole Treatment for Eradication of Helicobacter pylori.- Eradication of Helicobacter pylori Cures Duodenal Ulcer Disease.- Two-Month Assessment of Duodenal Ulcer Healing and Helicobacter pylori Eradication Rates in Patients Treated for One Month with Omeprazole Alone or Combined with Antibiotics.- Helicobacter pylori and Healing of Refractory Duodenal Ulcer: Preliminary Results of a Randomised Trial.- Treatment with Amoxicillin and Colloidal Bismuth Subcitrate in Children with Helicobacter pylori-Associated Peptic Disease.- Helicobacter pylori and Duodenal Ulcer Relapse: Effect of Bismuth-Free Short-Term Triple Therapy.- Bismuth Subnitrate in Comparison to Ranitidine in Patients with Non-ulcer Dyspepsia: A Randomized Controlled Trial.- Colloidal Bismuth Subcitrate Versus Amoxicillin in the Treatment of Helicobacter pylori-Associated Type B Gastritis.- Response of Helicobacter pylori-Associated Gastritis to Colloidal Bismuth Subcitrate Versus Ranitidine in Patients with Duodenal Ulcer: A Detailed Histological Assessment.- Eradication of Helicobacter pylori: Summary of Workshop.- Treatment of Helicobacter pylori Infection: Challenges and Future Prospects.