Hedgehog Signaling: Volume 88

ISBN-13: 9780123946225 / Angielski / Twarda / 2012 / 584 str.

Gerald Litwack

Opis

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on hedgehog signaling.

• Contributions from leading authorities
• Informs and updates on all the latest developments in the field

Spis treści

1. Hedgehog Signaling

Siu Wah Choy, Shuk Han Cheng

2. Canonical and Non-Canonical Hedgehog/GLI Signaling in Hematological Malignancies

Fritz Aberger, Daniela Kern, Richard Greil and Tanja Nicole Hartmann

3. Non-Canonical Hedgehog Signaling

Donna Brennan, Xiaole Chen, Lan Cheng, My Mahoney, and Natalia A Riobo

4. Gli Protein Nuclear Localization Signal

Minoru Hatayama and Jun Aruga

5. Mammalian Homologues of Drosophila Fused Kinase

Alla Maloverjan and Marko Piirsoo

6. Identification, Functional Characterization and Pathobiological Significance of GLI1 Isoforms in Human Cancers

Richard L. Carpenter, Hui-Wen Lo

7. Gli-Similar (Glis) Proteins: Their Mechanisms of Action, Physiological Functions, and Roles in Disease

Kristin Lichti-Kaiser, Gary ZeRuth, Hong Soon Kang, Shivakumar Vasanth, and Anton M. Jetten

8. Sonic Hedgehog Regulates Wnt Activity During Neural Circuit Formation

Nicole H. Wilson and Esther T. Stoeckli

9. Hedgehog/Gli Control by Ubiquitination/Acetylation Interplay

Alberto Gulino, Lucia Di Marcotullio, Gianluca Canettieri, Enrico Desmaele, Isabella Screpanti

10. Palmitoylation of Hedgehog Proteins

John A. Buglino and Marilyn D. Resh

11. Phosphorylation Regulation of Hedgehog Signaling

Jianhang Jia

12. Protein Kinase A Activity and Hedgehog Signaling Pathway

Tomoya Kotani

13. Phosphorylation of Gli by Camp-Dependent Protein Kinase

Yoshinari Asaoka

14. ZFP932 Suppresses Cellular Hedgehog Response and Patched1 Transcription

G. Jason Huang, Zhenhua He and Liang Ma

15. A New Era for an Ancient Drug; Arsenic Trioxide and Hedgehog Signaling

Elspeth M. Beauchamp and Aykut Üren

16. Aberrations and Therapeutics Involving the Developmental Pathway Hedgehog in Pancreatic Cancer

Fergal Crothur Kelleher

17. Sonic Hedgehog Signaling and Potential Therapeutic Indications

Nicholas C. Bambakidis, Kaine Onwuzulike

18. Sonic Hedgehog on Microparticles and Neovascularization

Raffaella Soleti and Maria Carmen Martinez

19. 'Patch'-ing Up the Neurons: Revival or Enervation?

Sayantani Ghosh, Arunabha Chakrabarti and Debashis Mukhopadhyay

20. Activation of Hedgehog Pathway in Gastrointestinal Cancers

Ling Yang, Xiulan Su, Jingwu Xie

21. The Role Of Sonic Hedgehog as a Regulator of Gastric Function and Differentiation

Rui Feng, Chang Xiao and Yana Zavros

22. Sonic Hedgehog-Mediated Synergistic Effects Guiding Angiogenesis and Osteogenesis

Sabine Fuchs, Eva Dohle, Charles James Kirkpatrick

23. Hedgehog Inhibition as an Anti-Cancer Strategy

G. Praveen Raju, and Diane Pham

O autorze

Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)