Health Consequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids

ISBN-13: 9783030151461 / Angielski / Twarda / 2020 / 493 str.

Howard Goldfine

Spis treści

Bacterial Adherence to Plant and Animal Surfaces Via Adhesin-Lipid Interactions.- Lipid Rafts in Bacteria: Structure and Function.- Lipids and Legionella Virulence.- Lipids of Clinically Significant Mycobacteria.- Mycobacterial Lipid Bodies and the Chemosensitivity and Transmission of Tuberculosis.- Role of Sphingolipids in Bacterial Infections.- Participation of Bacterial Lipases, Sphingomyelinases, and Phospholipases in Gram-negative Bacterial Pathogenesis.- Participation of Bacterial Lipases, Sphingomyelinases, and Phospholipases in Gram-Positive Bacterial Pathogenesis.- Methanotrophy, Methylotrophy, the Human Body, and Disease.- Skin: Cutibacterium (formerly Propionibacterium) acnes and Acne Vulgaris.- Hydrocarbon Degraders as Pathogens.- Antimicrobial Activity of Essential Oils.- Infection Prevention: Oil- and Lipid-Containing Products in Vaccinology.- Tuning Activity of Antimicrobial Peptides by Lipidation.- Gastrointestinal Tract: Fat Metabolism in the Colon.- Gastrointestinal Tract: Intestinal Fatty Acid Metabolism and Implications for Health.- Gastrointestinal Tract: Microbial Metabolism of Steroids.- Microbial Oils as Nutraceuticals and Animal Feeds.- Microbiome Metabolic Potency Towards Plant Bioactives and Consequences for Health Effects.- Poly-Beta-Hydroxybutyrate (PHB) and Infection Reduction in Farmed Aquatic Animals.-

O autorze

Dr. Howard Goldfine received his B.S. degree from the City College of the City University of New York and his Ph.D. from the University of Chicago. After postdoctoral fellowships in the laboratories of Earl Stadtman at the NIH and Konrad Bloch at Harvard University, he joined the faculty of the Department of Microbiology and Immunology at Harvard Medical School. He moved to the University of Pennsylvania as an Associate Professor of Microbiology in the School of Medicine and subsequently was promoted to Full Professor. He has held a Macy Foundation Faculty Scholar Award, a Fogarty Senior International Fellowship, and a fellowship from the Japan Society for the Promotion of Science and has been a Visiting Professor at the University of Basel and University College London. He is President of the newly organized International Plasmalogen Society. In recognition of his research accomplishments he was elected a Fellow of the American Academy of Microbiology in 1988 and of the American Association for the Advancement of Science in 1998.

Dr. Goldfine has had a notable career in biochemistry and microbiology over the past half century. During this time he has made important contributions to our understanding of bacterial fatty acid and phospholipid biosynthesis, the assembly of the outer membranes of Gramnegative bacteria, the regulation of biophysical properties of bacterial membranes, and the structures, biosynthesis, and functions of bacterial ether lipids. In a second major phase of his research career his laboratory played a large role in elucidating the roles of phospholipases in bacterial pathogenesis with a focus on Listeria monocytogenes.