1 Risk Factors for Venous Thromboembolism 3 Peter E. Rose
2 Management of Venous Thrombosis in the Lower Limbs 13 Dan Horner
3 Clinical Presentation of Acute Pulmonary Embolism 21 C.E.A. Dronkers, M.V. Huisman and F.A. Klok
Section II Diagnosis 27
4 Clinical Prediction Scores 29 Kerstin de Wit and Lana A. Castellucci
5 Laboratory Aspects in Diagnosis and Management of Venous Thromboembolism 35 Giuseppe Lippi and Emmanuel J. Favaloro
6 Thrombophilia Testing 49 Massimo Franchini
7 Radiological Diagnosis of Pulmonary Embolism 55 Joachim E. Wildberger and Marco Das
8 The Antiphospholipid Syndrome 60 Karen Breen
Section III Treatment 67
9 Inpatient or Outpatient Anticoagulation 69 Lauren Floyd and Jecko Thachil
10 An Anticoagulant Service in Practice 73 Kathy Macintosh, Dawn Kyle and Linda Smith
11 Point of Care Testing 86 Dianne Patricia Kitchen
12 Direct Oral Anticoagulants in the Prevention and Management of Venous Thromboembolism 94 Yen]Lin Chee and Henry G. Watson
13 The Role of Thrombolysis in the Management of Venous Thromboembolism 102 Carlos J. Guevara and Suresh Vedantham
14 Inferior Vena Cava Filters in the Management of Venous Thromboembolism 114 Anita Rajasekhar and Molly W. Mandernach
Section IV Special Situations 129
15 VTE in Pregnancy 131 Catherine Nelson Piercy
16 Paediatric Venous Thromboembolism 145 Paul Monagle and Rebecca Barton
17 Cancer]associated Thrombosis 153 Simon Noble
18 Venous Thromboembolism Management in Obese Patients 161 Kathryn Lang and Jignesh Patel
19 Venous Thromboembolism in Intensive Care 169 Gill Parmilan and Jecko Thachil
20 Venous Thromboembolism; a Primary Care Perspective 174 David Fitzmaurice
Section V Unusual Site Thrombosis 181
21 Cerebral Venous Thrombosis 183 Christian Weimar
22 Upper Extremity Thrombosis 192 Scott M. Stevens and Scott C. Woller
23 Management of Intra]abdominal Thrombosis 205 Serena M. Passamonti, Francesca Gianniello and Ida Martinelli
24 Thrombosis in the Retinal Circulation 216 Wenlan Zhang and Paul Hahn
Section VI Long]term Sequelae of VTE 229
25 Post]thrombotic Syndrome 231 Andrew Busuttil and Alun H. Davies
26 Chronic Thromboembolic Pulmonary Hypertension 240 Demosthenes G. Papamatheakis and William R. Auger
27 Predicting Recurrent VTE 255 R. Campbell Tait
Section VII Controversies 263
28 Cancer Screening in Unprovoked Venous Thromboembolism 265 David Keeling
29 Sub]segmental and Incidental PE – to Treat or Not? 269 Jecko Thachil
30 Management of Distal Vein Thrombosis 273 Giuseppe Camporese and Enrico Bernardi
Section VIII Prevention 281
31 A Summary of the Evidence for VTE Prevention, with a Focus on the Controversies 283 Catherine Bagot
32 VTE Prevention: Real World Practice 293 Emma Gee
33 VTE Root Cause Analysis – How To Do It 301 Alison Moughton, Francesca Jones and Will Lester
Index
JECKO THACHIL, MBBS, MD, MRCP, FRCPath is a consultant haematologist at Department of Haematology, Manchester Royal Infirmary in Manchester, UK. He has a special clinical interest in blood coagulation disorders and the prevention and treatment of venous thrombosis. He is the editor of the Wiley–Blackwell publication Haematology in Critical Care.
CATHERINE BAGOT, BSc, MBBS, MD, MRCP, FRCPath is a consultant haematologist at Department of Haematology, Glasgow Royal Infirmary in Glasgow, UK. He specializes in haemostasis and thrombosis at Glasgow Royal Infirmary and who is mainly interested in the role of thrombin generation in thrombosis risk stratification.
A Clinically Oriented Handbook Providing Up–to–Date Recommendations for Mastering the Practical Aspects of Patient Management for Venous Thromboembolism
Venous thromboembolism (VTE) is associated with high morbidity and mortality both in and out of the hospital setting and is one of the commonest reasons for hospital attendances and admissions. Designed as a practical resource, the Handbook of Venous Thromboembolism covers the practical aspects of VTE management in short and easily followed algorithms and tables. This important text helps keep physicians up to date with the latest recommendations for treating VTE in clinic–oriented settings. Experts in fields such as the radiological diagnosis of pulmonary embolism and thrombophilia testing give a summary of investigation, diagnosis and treatment of VTE and include evidence–based guidelines.
With contributions from a team of internationally recognized experts, the Handbook of Venous Thromboembolism is a source of information that specialists in the field can recommend to non– specialists and that the latter will be able to review to assist in their education and management of this widespread condition. This vital resource:
Provides a clinically focused daily resource for the busy physician
Is written by an international team of specialists who offer their experience on the practical aspects of VTE management
Addresses venous thrombosis prevention, a major focus for healthcare providers
Includes a coverage on controversies in the management of VTE to enable clinicians to understand how experts are practicing in real scenarios
Written for haematology trainees, emergency and acute medicine physicians, junior doctors, and primary care physicians, the Handbook of Venous Thromboembolism covers the basics for treating patients with venous thromboembolism and offers guidelines from noted experts in the field.