Handbook of Research on Medicinal Chemistry: Innovations and Methodologies

ISBN-13: 9781771885447 / Angielski / Twarda / 2017 / 626 str.

Debarshi Kar Mahapatra; Sanjay Kumar Bharti

Opis

This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals. The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals. The volume many important aspects of medicinal chemistry, including

• techniques in drug discovery
• pharmacological aspects of natural products
• chemical mediators: druggable targets
• advances in medicinal chemistry

The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration.. Topics include:

• drug design
• drug discovery
• natural products and supplements and nutraceuticals
• pharmaceutical approaches to sexual dysfunction
• drug resistance parasites
• new natural compounds and identification of new targets
• stereochemistry aspects in medicinal chemistry
• common drug interactions in daily practices

Handbook of Research on Medicinal Chemistry: Innovations and Methodologies will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.

Spis treści

Combinatorial Chemistry: Role in Lead Discovery. Advanced Techniques in Bimolecular Simulations. Retrometabolic Drug Design. Insight Into The Pharmacological Potentials of Camellia sinensis Linn. Pharmaceutical Importance of Natural Aphrodisiac Drugs. Serotonin: Chemical, Biological and Therapeutic Aspects. Eicosanoids: Constitution and Pathophysiological Functions. Development of Antimalarial Drug Analogues to Combat Plasmodium Resistance. Chemistry and Pharmacology of Β-Lactam Analogues. General Anaesthetics. Stereochemical Aspects in Medicinal Chemistry. Pharmaceutical Interactions in Drug Practices.

O autorze

Debarshi Kar Mahapatra, PhD, is currently an Assistant Professor at Department of Pharmaceutical Chemistry, Kamla Nehru College of Pharmacy, RTM Nagpur University, Nagpur, India. He taught medicinal and computational chemistry at both the undergraduate and postgraduate levels and has mentored students in their various research projects. His area of interest includes computer-assisted rational designing and synthesis of low molecular weight ligands against druggable targets, drug delivery systems, and optimization of unconventional formulations. He has published research, book chapters, reviews, and case studies in various reputed journals and has presented his works at several international platforms, for which he received several awards by a number of bodies. He has also authored a book titled Drug Design. Presently, he is serving as reviewer and editorial board member for several journals of international repute. He is a member of a number of professional and scientific societies, such as the International Society for Infectious Diseases (ISID), the International Science Congress Association (ISCA), and ISEI.

Sanjay Kumar Bharti, PhD, is an Assistant Professor in Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur. He has working experience in several organizations, such as Win-Medicare Pvt. Ltd, Meerut, India (as a chemist) and the National Institute of Pharmaceutical Education and Research (NIPER), Hajipur (as a lecturer). He has published several research papers, one book, several book chapters and review articles in various reputed journals. His research interest includes synthesis of Schiff’s base, heterocyclic compounds, and metallopharmaceuticals for therapeutics. He is an active member of various scientific and pharmaceutical organizations like IPA, IPGA, ISCA, etc. Dr. Bharti has completed a BPharm from IT-BHU, Varanasi, India, in 2003, an M.Pharm from RGPV, Bhopal, India, in 2004, and a PhD from IIT-BHU, Varanasi, India, in 2011.