Handbook of Juvenile Idiopathic Arthritis

ISBN-13: 9783319081014 / Angielski / Miękka / 2015 / 124 str.

Ravelli, Angelo

Opis

Handbook of Juvenile Idiopathic Arthritis

Spis treści

Introduction 

Disease overview

Epidemiology

Etiology and pathogenesis

Environmental factors

Genetic susceptibility

Role of humoral and cell-mediated immunity

Pathogenesis of systemic arthritis

Pathophysiology of macrophage activation syndrome

Disease classification 

Classification criteria 

Challenges in classification

Clinical manifestations 

Systemic arthritis 

Rheumatoid factor-negative polyarthritis 

Rheumatoid factor-positive polyarthritis 

Oligoarthritis 

Enthesitis-related arthritis 

Psoriatic arthritis 

Undifferentiated arthritis 

Diagnosis 

Clinical assessment 

Imaging 

Biomarkers 

Differential diagnosis

Consequences and complications 

Disease course of different subtypes 

Skeletal and growth abnormalities 

Ophthalmologic complications 

Macrophage activation syndrome 

General treatment aspects

Goals of treatment 

Measuring treatment response 

Treatment recommendations 

A multidisciplinary approach to treatment 

Special considerations in the pediatric patient 

Management of patients with

juvenile idiopathic arthritis 

Psychosocial factors 

Physical therapy 

Other non-pharmacologic interventions 

Non-steroidal anti-inflammatory drugs 

Intra-articular corticosteroids 

Systemic corticosteroids 

Conventional disease-modifying anti-rheumatic drugs 

Biologic disease-modifying anti-rheumatic drugs 

Safety of biologics 

Other pharmacologic interventions 

Management of iridocyclitis 

Management of macrophage activation syndrome 

Specific issues 

Health-related quality of life 

Vaccination 

Treatment discontinuation after disease remission

Transition to adult care

Outcome, prognosis and future outlook 

Long-term outcome and its prediction 

Mortality 

Future outlook 

     

O autorze

Angelo Ravelli is Associate Professor of Pediatrics at the School of Medicine of the University of Genoa, Italy, a position held since 2006. He is Chief of the Centre of Clinimetrics of the Istituto Giannina Gaslini of Genoa, Italy, a position he has held since 2012. Previously, he was Chief of the Interventional Rheumatology Unit at the same institution. After completion of a degree in medicine, Dr Ravelli specialized in paediatrics and allergology. His field of clinical and research activity focuses on paediatric rheumatology.

Dr Ravelli has been invited to speak in more than 200 national and international meetings and has published more than 220 full-length articles in international scientific journals, with a total impact factor of more than 1,200 and an h-index of 43. He has received numerous grants and awards, including the Gerolamo Prize for Excellence in Research in 2004. He is Associate Editor of Pediatric Rheumatology Online Journal, Assistant Editor of Clinical and Experimental Rheumatology and serves on the Editorial Board of The Journal of Rheumatology and Arthritis Care & Research. He is a member of the Executive Committee of the European Rheumatology Research Foundation and was Chairman of the Lupus Working Group of the Pediatric Rheumatology European Society (PReS) from 2004 to 2010.