Handbook of Drug Interactions: A Clinical and Forensic Guide

ISBN-13: 9781588292117 / Angielski / Twarda / 2003 / 663 str.

Ashraf Mozayani; Lionel P. Raymon

Opis

A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents.
Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.

Recenzje

"This book offers a comprehensive guide to drug interactions and has particular utility in both the educational and clinical environments. In the academic arena it offers some insights to the legal implications not discussed on other resources. This book would also make a valuable addition to the clinical library. . .It is organized by drug class, with the major classes represented, including CNS drugs, cardiovascular agents, antibiotics and nonsteroidal anti-inflammatory agents. A unique section covers environmental and social pharmacology issues with regards to drug interactions, including the influence of food, alcohol, tobacco, and anabolic agents. One of the more unique features of the book are the two final chapters that address litigation regarding drug interactions and psychotropic medications and crime. Tables are extensively and wisely used throughout to present large amounts of drug interaction data in an appropriate synopsis for quick reference. Illustrations of chemical structures to elucidate pharmacological interactions are appropriately used." -Doody's Health Sciences Book Review Journal

"The book is effective in gathering information about several classes of drugs in one volume...Recommended." -E-STREAMS

"...a welcome addition...I would recommend this text as a useful reference to students, researchers and physicians alike." - BTS Newsletter

Spis treści

Part I. Central Nervous System Drugs Chapter 1: Drug Interactions with Benzodiazepines: Epidemiologic Correlates with Other CNS Depressants and In Vitro Correlates with Inhibitors and Inducers of Cytochrome P450 3A4 David E. Moody Chapter 2: Antiepileptic Drugs Nathan L. Kanous II and Barry E. Gidal Chapter 3: Opioids and Opiates Seyed-Adel Moallem, Kia Balali-Mood, and Mahdi Balali-Mood Chapter 4: Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Terry J. Danielson Chapter 5: Selective Serotonin Reuptake Inhibitors Mojdeh Mozayani and Ashraf Mozayani Chapter 6: Antipsychotic Drugs and Interactions: Implications for Criminal and Civil Litigation Michael Welner Part II. Cardiovascular Drugs Chapter 7: Cardiovascular Drugs Johann Auer Part III. Antibiotics Chapter 8: Antimicrobial Drugs Amanda J. Jenkins and Jimmie L. Valentine Chapter 9: Drug Interactions with Medications Used for HIV/AIDS Michael Frank Part IV. Nonsteroidal Antiinflammatory Drugs Chapter 10: Nonsteroidal Antiinflammatory Drugs: Cyclooxygenase Inhibitors, Disease-Modifying Antirheumatic Agents, and Drugs Used in Gout Imad K. Abukhalaf, Daniel A. von Deutsch, Mohamed A. Bayorh, and Robin R. Socci Part V. Environmental and Social Pharmacology Chapter 11: Food and Drug Interactions Shahla M. Wunderlich Chapter 12: Alcohol and Drug Interactions A. Wayne Jones Chapter 13: Nicotine and Tobacco Edward J. Cone, Reginald V. Fant, and Jack E. Henningfield Chapter 14: Anabolic Doping Agents Daniel A. von Deutsch, Imad K. Abukhalaf, and Robin R. Socci Part VI. Legal Aspects Chapter 15: Drug Interaction Litigation Stephen A. Brunette Chapter 16: Psychotropic Medications and Crime: The Seasoning of the Prozac Defense Michael Welner Index

Blurb

Drug interactions and adverse drug effects are responsible for the hospitalization and extended hospitalization of more than 100,000 Americans annually, not to mention a significant number of deaths. In Handbook of Drug Interactions: A Clinical and Forensic Guide, leading drug experts from pharmacology, toxicology, medicine, nutrition, and law have compiled a concise record of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. The authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions for each class of drugs. Where necessary, they also consider forensic factors and implications for criminal law, malpractice, and tort litigation. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Individual chapters are devoted to drug interaction litigation and the role of psychotropic medications in crime. A detailed index provides rapid access to the book's extensive information on potential interactions.
Comprehensive and thorough, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and those active in clinical chemistry and laboratory medicine with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.