Handbook of Clinical Electrophysiology of Vision

ISBN-13: 9783030304195 / Angielski / Miękka / 2021 / 219 str.

Minzhong Yu; Donnell Creel; Alessandro Iannaccone

Recenzje

"This is a well-written comprehensive text for those interested in the clinical electrophysiology of vision. It will also assist in treating degenerative or toxic retinopathies, monitoring treatment effect and side effect of medicines, and guidance to all levels of practitioners." (Etienne M. Schönbach, Marwan Abdulaal, Lalita Gupta, Lily Kim and Shree K. Kurup, Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 258, 2020)

Spis treści

​PART 1.  Basic Theory of Electrophysiology of Vision

Chapter 1. ELECTRORETINOGRAMS

Donnell J. Creel and Minzhong Yu

1.1 Components of ERG.

1.2 Types of ERG

1.2.1 Full-field ERG

1.2.1.1. Dark-adapted rod-driven scotopic and mixed flash ERGs.

1.2.1.2. Light-adapted cone-driven ERG

1.2.2 Pattern ERG

1.2.3 Multifocal ERG

1.2.4 Focal flash ERG  

1.3 Electrodes, stimulation and recording methods 

1.3.1 ERG electrodes

1.3.2 Stimulation

1.3.3 Recording method

1.3.3.1 Dilation, dark-adaptation and topical anesthesia

1.3.3.2 Testing infants

1.3.4 Advanced analysis of ERG data

1.3.4.1. Intensity-response function of ERG b-wave

1.3.4.2. Oscillatory Potentials (OPs) Analysis

Chapter 2. VISUALLY EVOKED POTENTIALS

Donnell J. Creel and Minzhong Yu

2.1 Origins of VEP components

2.2 Electrode placement

2.3 Amplifier and analysis

2.4 Types of VEP

2.4.1. Steady-state and transient VEP

2.4.2. Flash and pattern VEP

2.4.3. Multifocal VEP

2.5 Clinical protocol

Chapter 3. Electrooculography (EOG) 

Donnell J. Creel and Minzhong Yu

3.1 Origin of EOG

3.2 Placement of recording electrodes, parameters of amplifier and stimulation

3.3 Recording procedure

PART 2.  Clinical Application of Electrophysiology of Vision

Chapter 4: Congenital non-degenerative retinal diseases

Wajiha Kheir, MD; Roberto Gattegna, MD; Minzhong Yu, PhD; Alessandro Racioppi, BS; Alfonso Senatore, MD; Donnell Creel, PhD;  Alessandro Iannaccone, MD, MS, FARVO

 4.1 Night Blinding disorders

4.1.1. Congenital stationary night blindness

4.1.2. Oguchi disease

4.1.3. Fundus albipunctatus

4.2. Photophobia disorders

4.2.1. Achromatopsia (ACHM) and Blue Cone Monochromatism (BCM)

4.2.2. Phenotypes associated with mutations in the paired box 6 gene 

Chapter 5. Macular dystrophies

Wajiha Kheir, MD; Minzhong Yu, PhD; Alfonso Senatore, MD; Roberto Gattegna, MD; Alessandro Racioppi, BS; Donnell Creel, PhD; Alessandro Iannaccone, MD, MS, FARVO

 5.1. Stargardt’s disease/fundus flavimaculatus. 

5.2. X-linked retinoschisis

5.3. Vitelliform macular dystrophy (Best’s disease)

5.4. Pattern Dystrophies/Macular pattern dystrophy (MPD)

5.5. Doyne’s Honeycomb Macular Dystrophy (Malattia Leventinese)  

5.6. Occult Macular Dystrophy 

5.7. North Carolina Macular Dystrophy (NCMD)

Chapter 6. Degenerative night-blinding disorders and cone and cone-rod dystrophies

Wajiha Kheir, MD;  Minzhong Yu, PhD; Alfonso Senatore, MD; Alessandro Racioppi, BS; Roberto Gattegna, MD; Donnell Creel, PhD; Alessandro Iannaccone, MD, MS, FARVO 

6.1. Retinitis pigmentosa

6.2. Leber's congenital amaurosis / EORP / SECORD

6.3. Enhanced S-Cone syndrome

6.4. Choroideremia

6.5. Gyrate atrophy of choroid and retina

6.6. Late onset retinal degeneration (L-ORD) 

6.7. Bietti’s crystalline dystrophy    

6.8. Cone dystrophies

6.9. Cone-rod dystrophies

Chapter 7. Syndromic disorders 

Alfonso Senatore, MD; Wajiha Kheir, MD; Minzhong Yu, PhD; Alessandro Racioppi, BS; Roberto Gattegna, MD; Donnell Creel, PhD; Alessandro Iannaccone, MD, MS, FARVO 

7.1. Hearing loss syndromes

7.1.1. Usher syndrome 

7.1.2. Refsum disease 

7.1.3. Wolfram syndrome (DIDMOAD) 

7.2. Mitochondrial diseases

7.2.1. Kearns-Sayre syndrome

7.2.2. Neuropathy-Ataxia-Retinitis Pigmentosa syndrome

7.2.3. Maternally-Inherited Diabetes and Deafness syndrome 

7.3. Obesity syndromes and 

7.3.1. Bardet-Biedl syndrome

7.3.2. Alström syndrome  

7.3.3. Cohen syndrome

7.4. Other Syndromes 

7.4.1. Cockayne syndrome

7.4.2. Alagille syndrome (arteriohepatic dysplasia)

7.4.3. Senior-Loken Syndrome 

7.4.4. Joubert Syndrome

7.5. Metabolic disorders

7.5.1. Abetalipoproteinemia (Bassen-Kornzweig syndrome) 

7.5.2. Neuronal Ceroid Lipofuscinoses (Batten’s disease)

7.5.3. Mucopolysaccharidosis 

Chapter 8. Characteristics of Visual Electrophysiology in Inflammatory Disorders

Alessandro Iannaccone, Alfonso Senatore, Wajiha Jurdi Kheir, Donnell J. Creel and Minzhong Yu

8.1. Acute zonal occult outer retinopathy (AZOOR)

8.2. Multiple Evanescent White Dot Syndrome

8.3. Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)

8.4. Birdshot chorioretinopathy 

8.5. Autoimmune retinopathy and neuroretinopathy 

Chapter 9. Characteristics of Visual Electrophysiology in Retinal Toxicities

Minzhong Yu, Alfonso Senatore, Alessandro Iannaccone, Wajiha Jurdi Kheir, and Donnell J. Creel

9.1. Vigabatrin 

9.2. Hydroxychloroquine (Plaquenil) and chloroquine

9.3. Antipsychotics 

9.4. Cis-platinum

9.5. Deferoxamine

9.6. Digoxin

9.7. Ethambutol

9.8. Indomethacin

9.9. Isotretinoin

9.10. Ocular siderosis

9.11. Phosphodiesterase type (PDE) 5 inhibitors (Erectile dysfunction medication) 

9.12. Quinine

Chapter 10. Characteristics of Visual Electrophysiology in the Diseases of Optic Nerve or Visual Pathway

Minzhong Yu and Donnell J. Creel

10.1. Multiple sclerosis

10.2. Ischemic optic neuropathy

10.3. Optic neuritis

10.4. Optic nerve hypoplasia

10.5. Traumatic optic neuropathy

10.6. Neurofibromatosis

10.7. Optic nerve toxicities

10.7.1. Ethambutol

10.7.2. Neonatal hyperbilirubinaemia

10.7.3. Radiotherapy

10.8. Leber's hereditary optic neuropathy

10.9 Amblyopia

Chapter 11. Characteristics of Visual Electrophysiology in Albinism    

Donnell J. Creel, Minzhong Yu, and Alessandro Iannaccone     

O autorze

Minzhong Yu, PhD, MMed

University Hospitals Eye Institute

Cleveland, Ohio

USA 

Donnell J. Creel, PhD

Moran Eye Center

University of Utah School of Medicine

65 Mario Capecchi Drive

Salt Lake City, UT 84132

USA

Alessandro Iannaccone, MD, MS, FARVO

Center for Retinal Degenerations and Ophthalmic Genetic Diseases  

Duke University School of Medicine

Duke Eye Center, Department of Ophthalmology

Durham, North Carolina

USA

Blurb

This book provides an analytical and thorough review of clinical electrophysiology of vision, and the progress made in the field in the past decade. Handbook of Clinical Electrophysiology of Vision is designed to aid the readers in understanding the types of electrophysiologic tests that should be used in specific diseases, how to explain the results of these exams, and how to perform the tests of clinical electrophysiology of vision. 

Concise in format, the Handbook of Clinical Electrophysiology of Vision is divided into two sections that discuss a wide range of relevant topics, such as technology of electroretinography, electrooculography, visual evoked potential, characteristics of electroretinography in retinal diseases, and the characteristics of optic nerve diseases. Part one begins with a discussion on the basic theory of electrophysiology of vision, illustrating physiologic sources of electrophysiological responses, the techniques of the recording, and analysis of electrophysiologic signals. Part two then dives into the clinical application of electrophysiology of vision, and subsequently summarizes the characteristics of the electrophysiological signals in a number of disorders of retina and optic nerve. 

Written by experts in the field, Handbook of Clinical Electrophysiology of Vision is an invaluable resource for ophthalmologists, optometrists, electrophysiologists, residents, fellows, researchers, technicians and students in ophthalmology, optometry and vision science.