Handbook of Bioethical Decisions. Volume I: Decisions at the Bench

ISBN-13: 9783031294501 / Angielski

Erick Valdés; Juan Alberto Lecaros

Opis

The Handbook of Bioethical Decisions is aimed at addressing and analyzing the most important ethical concerns and moral quandaries arisen in biomedical and scientific research. As such, it identifies and problematizes on a comprehensive range of ethical issues researchers must deal with in different critical contexts. Thus, the Handbook, Vol. I, may be helpful for them to make decisions and deliberate in complex practical scenarios. In this fashion, the volume reunites different points of view to give readers room enough to get a better knowledge and take their own position on pressing bioethical issues of the day. Consequently, this work seeks to engender dense ethical epistemology scientists can count on when conducting latest generation biomedical research. By bringing together an impressive array of contributions on the most important elements and categories for “at the bench” bioethical decisions as well as offering chapters by some of the most world renowned and prominent experts in bioethics, the Handbook, Vol. I, is a paradigmatic text in its area and a valuable resource for courses on bioethics, and biomedical research, as well as courses that discuss ethics and the biosciences at different professional levels, biomedical industry, pharmacological companies and the public sphere in general. 

Spis treści

Foreword - Peter Singer.-

Introduction

Biomedical Research in One World: Current and Future Challenges.-

Erick Valdés and Juan Alberto Lecaros 

Part I - Biomedical Research

Section One - Genetic and Cell Research

Chapter 1

Learning from Icarus: The Impact of CRISPR on Gene Editing Ethics.- 

Brendan Parent

Chapter 2

Bioethical Decision Making and Genome Editing.- 

Calum MacKellar

Chapter 3

Therapeutic Genome Editing.- 

Ellen Wright Clayton

Chapter 4

Bioethical Decision-Making about Somatic Cell Genome Editing: 

Sickle-Cell Disease as a Case Study.- 

Christopher Rudge and Dianne Nicol

Chapter 5

Gene Therapy and Germline Cells Research.- 

Ferdinando A. Insanguine Mingarro

Chapter 6

Bioethical Quandaries in Preimplantation Genetic Diagnosis.- 

Erick Valdés

Chapter 7

Rare Disease Research.- 

Francesc Palau and Carmen Ayuso

Chapter 8

Limits of Debate: Governance of Human Embryo Research and 

the Making of the Fourteen-Day Rule.- 

J. Benjamin Hurbult

Chapter 9

Human/Non-Human Chimeras.- 

Iñigo de Miguel Beriain

Chapter 10

Human Cloning: Recent Advances and Bioethical Issues.- 

Sidra Shafique

Section Two - Enhancement Research.- 

Chapter 11

The Evolutionary Optimality Challenge.- 

Nick Bostrom, Anders Sandberg and Matthew van der Merwe

Chapter 12

Mood Enhancement.- 

Daniel Loewe

Chapter 13

Superior Sport Performance: Ethical and Legal Issues.- 

Elena Atienza Macías

Chapter 14

Arguments over Life Extension in Contemporary Bioethics.- 

Allen Porter

Section Three - Research with Human Biological Samples and Health Data.-

Chapter 15

Research with Human Biological Samples.  Systematization of

the Phases and Affected Rights.- 

Pilar Nicolás

Chapter 16

Biobanks for Biomedical Research: Evolution and Future.- 

Juan Alberto Lecaros

Chapter 17

Biobanking in Global Health & Research.- 

Jonathan W. Ashcroft, and Cheryl Macpherson

Chapter 18

Ethical and Legal Considerations in Genomic Data Sharing: 

Evolution of the Discourse and the Road Ahead.- 

Adrian Thorogood and Davit Chokoshvili

Section Four - Biomedical Challenges in Research.- 

Chapter 19

Human Challenge Trials in Pandemics: Risks and Benefits.- 

Erick Valdés

Chapter 20

Ethical Considerations for Vaccine Research.- 

Ricardo Palacios

Chapter 21

Global Health Partnerships and Emerging Infectious Disease.- 

Nancy S. Jecker 

Chapter 22

Precision Medicine.- 

Fruzsina Molnár-Gabór

Chapter 23

The Development, Implementation, and Oversight of Artificial 

Intelligence in Health Care: Legal and Ethical Issues.- 

Jenna Becker, Sara Gerke, and I. Glenn Cohen

Part II - Animals, Food and Environment.-

Section One - Using Animals in Scientific Research.-

Chapter 24

The Use of Animals in Basic Biological Research.- 

Monica Levy Andersen and Daniela Santoro Rosa

Chapter 25

The Use of Animals in the Study of Human Disease: 

Key Roles of General Ethical Principles.- 

Jerrold Tannenbaum

Chapter 26

Ethical Issues Concerning Genetically Modified Animals 

for the Study of Human Diseases.- 

Eduardo Rodríguez Yunta

Chapter 27

Of Mice-Rats and Pig-Men: Ethical Issues in the Development 

of Human/Nonhuman Chimeras.- 

Mackenzie Graham

Chapter 28

Animals in Research in Pharmaceutical Industry.- 

Margaret S. Landi

Chapter 29

Animal Use in Toxicity Studies.- 

Andrew Rowan

Chapter 30

Ethical Issues from the Use of Animals in the Cosmetics 

and Fashion Industries.- 

Darryl R. J. Macer

Chapter 31

Is it Time to Phase Out the Use of all Nonhuman Primates 

in Invasive Research?.- 

Bernardo Aguilera and Javiera Perez Gomez

Chapter 32

Growing Human Organs Inside Animals.- 

Julian Koplin and Neera Bhatia

Chapter 33

Animal Cloning.- 

Andrew J. French, and Alan Trounson

Section Two - Decision Making and Alternatives to Animal Use in Research.- 

Chapter 34

Replacement, Reduction and Refinement.- 

Tamara Tadich and Ariel Tarazona

Chapter 35

Integrating Human and Nonhuman Research Ethics.- 

Jeff Sebo

Chapter 36

Regulation of Animal Research.- 

Emilio A. Herrera

Section Three - GMOs for Global Challenges.-

Chapter 37

Ethical Issues in Genetically Modified Foods: From Transgenesis to CRISPR-Cas9 Genome Editing Technology.-

Erick Valdés and Juan Alberto Lecaros

Chapter 38

GMOs and Human and Environmental Safety.- 

Ignacio Chapela and Angelika Hilbeck 

Chapter 39

GMOs and Sustainable Agriculture.- 

Sheldon Krimsky

O autorze

Erick Valdés, Ph.D., is Professor of Bioethics and Biolaw, and Senior Research Scholar at the Institute of Science and Innovation in Medicine (ICIM), Universidad del Desarrollo (UDD), Santiago, Chile. He has served as Adjunct Research Professor of Bioethics at Georgetown University, USA; Adjunct Professor of Bioethics at American University, USA, and George Mason University, USA; Associate Professor of International Human Rights at the Washington Center for Internships and Academic Seminars, USA; and as Visiting Professor at Princeton University, USA. He is President and Founding Member of the International Network of Biolaw. His most recent books are Biolaw, Economics and Sustainable Governance. Addressing the Challenges of a Post-Pandemic World (Routledge, 2022), together with Jacob Dahl Rendtorff; Biolaw: Origins, Doctrine and Juridical Applications on the Biosciences (Springer, 2021); and Bioderecho. Epistemologías y aplicaciones en tiempos de pandemia y riesgo existencial (Tirant lo Blanch, 2021). He also published, together with Juan Alberto Lecaros, Biolaw and Policy in the Twenty-First Century. Building Answers for New Questions (Springer, 2019).

Juan Alberto Lecaros, Ph.D., is Associate Professor and Senior Research Scholar at the Institute of Science and Innovation in Medicine (ICIM), and Director of the Observatory of Bioethics and Law, Universidad del Desarrollo (UDD) Santiago, Chile. He has served as Visiting Professor at Ramón Llull University, Spain, and at University of the Basque Country, Spain. He is Founding Member of the International Network of Biolaw. He is the author of the forthcoming book Filosofía medioambiental: Principios y valores para una ciudadanía ecológica (Comillas, 2023). In 2019, he published, together with Erick Valdés, Biolaw and Policy in the Twenty-First Century. Building Answers for New Questions (Springer), and Ética animal: Fundamentos empíricos, teóricos y dimensión práctica (Comillas), with Bernardo Aguilera and Erick Valdés. He also published Bioética: el pluralismo de la fundamentación (Comillas, 2016), with other two editors.